Lipid peroxidation is associated with poor control of type-2 diabetes mellitus.

Background: Hyperglycemia increases oxidative stress through the overproduction of reactive oxygen species, which results in an imbalance between free radicals and the antioxidant defense system of the cells. A positive correlation was reported between lipid peroxide levels and diabetic complication.

Objectives: The aim of the present study was to investigate the state of oxidative stress in controlled and uncontrolled diabetic patients.

Relationship between oxidized low-density lipoprotein antibodies and obesity in different glycemic situations.

Background: Autoantibodies to oxidized low-density lipoprotein (oxLDL) are a heterogeneous group of antibodies that are controversially discussed to be either pathogenic or protective. Biochemical and anthropometric measurements correlated with increased levels of these antibodies are also controversial, especially in conditions of impaired glucose tolerance and type 2 diabetes mellitus. The present study was conducted to evaluate levels of oxLDL antibodies and their correlation with obesity in different glycemic situations.