Anti-microbial efficacy of L-glutaminase (EC 3.5.1.2) against multidrug-resistant Pseudomonas aeruginosa infection.

The aims of this study were isolation-purification and characterization of L-glutaminase from L. gasseri BRLHM clinical isolates and investigation of its efficiency as an antimicrobial agent against multidrug-resistant P. aeruginosa.

Corneal Perforation in a Patient Treated with Atezolizumab-Bevacizumab Combination Therapy for Unresectable Hepatocellular Carcinoma.

BACKGROUND Immune checkpoint inhibitors (ICIs) targeting the programmed cell death protein 1 (PD-1), or its ligand PD-L1, are the mainstay treatment for several metastatic malignant conditions. ICIs are associated with multiple toxic adverse events affecting various organs, known collectively as immune-related adverse events (irAEs). Dry eye, uveitis, ocular myasthenia, and cicatrizing conjunctivitis are well-recognized ocular irAEs associated with ICIs.

Microbial production of docosahexaenoic acid (DHA): biosynthetic pathways, physical parameter optimization, and health benefits.

Omega-3 fatty acids, including docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA), and α-linolenic acid (ALA), are essential polyunsaturated fatty acids with diverse health benefits. The limited conversion of dietary DHA necessitates its consumption as food supplements. Omega-3 fatty acids possess anti-arrhythmic and anti-inflammatory capabilities, contributing to cardiovascular health.

Salmon patch-like conjunctival lesion secondary to long-term administration of topical brimonidine: A case report.

Introduction: Brimonidine is a commonly used intra-ocular pressure-lowering agent for glaucoma patients. Allergic follicular or papillary conjunctivitis is a well-known side effect of brimonidine. Brimonidine is associated with ocular allergic symptoms such as conjunctival hyperemia, stinging sensation, photophobia and, in severe cases, corneal erosions.

Silver Nanoparticle Synthesis by Extract and Its Applicability against Foodborne Pathogens.

The consumption of foods polluted with different foodborne pathogens such as fungus, viruses, and bacteria is considered a serious cause of foodborne disease in both humans and animals. Multidrug-resistant foodborne pathogens (MRFP) cause morbidity, death, and substantial economic loss, as well as prolonged hospitalization. This study reports on the use of aqueous leaf extract (ARLE) in the synthesis of silver nanoparticles (ARLE-AgNPs) with versatile biological activities.

Three-years outcomes of simultaneous photorefractive surgery and customized corneal cross-linking for keratoconus.

Purpose: To report the efficacy of customized cross-linking (CXL) in halting progression of keratoconus when combined with photorefractive procedures.

Methods: Seven eyes from 7 patients with documented progressive keratoconus were treated with customized CXL (customized ultraviolet-A irradiance pattern centered on the maximum posterior elevation with total energy levels ranging from 5.4 up to 10 J/cm , and an energy fluence of 9 mW/cm) combined with photorefractive procedures.

The Relationship between Maternal Ideation and Exclusive Breastfeeding Practice among Saudi Nursing Mothers: A Cross-Sectional Study.

Unlabelled: All mortality risk factors are higher in non-breastfed infants compared to infants under five months of age who receive Exclusive Breastfeeding (EBF). Examining the predicting role of maternal ideation in EBF practices can help to direct and strengthen the cooperation between multidisciplinary healthcare providers to formulate multidisciplinary breastfeeding enhancement strategies.

Methods: This correlational cross-sectional study investigates the relationship between maternal ideation and EBF practice among Saudi nursing mothers at Maternal and Children's Hospital (MCH) in Najran, Saudi Arabia.

Public Knowledge, Attitude, and Practice Toward Vitamin D Deficiency in Al-Qunfudhah Governorate, Saudi Arabia.

Background: Vitamin D is a very important component of all vital functions in the human body. Its deficiency is a major public health issue worldwide and is associated with a broad spectrum of diseases. This study assessed knowledge, attitude, and practices regarding vitamin D deficiency among the general population in the Al-Qunfudhah governorate, Saudi Arabia.

Effect of Dry Heat Application on Perineal Pain and Episiotomy Wound Healing among Primipara Women.

Background: Women who undergo perineal episiotomy can be affected by several complications such as bleeding, infection, perineal pain, dyspareunia, reduction of sexual desire, as well as urinary and anal incontinence. Perineal pain related to episiotomy has been reported to interfere with women's daily activities postpartum and can prevent proper breastfeeding, proper rooming-in, and maternal-infant bonding. The purpose of this study was to determine the effect of dry heat application on perineal pain and episiotomy wound Healing among primipara women.

Infectious Keratitis in Corneal Graft following Astigmatic Keratotomy: A Case Report and Literature Review.

Femtosecond laser-assisted astigmatic keratotomy (FSAK) is recognized as a safe and effective therapeutic option for addressing high corneal astigmatism in corneal transplants. Although the incidence of corneal infection after FSAK in corneal transplants is very low, early detection and treatment is necessary to optimize visual outcomes and prevent devastating sequelae. This report describes a rare case of an early-onset infectious keratitis occurring in a corneal transplant after FSAK.

Antiviral peptides against SARS-CoV-2: therapeutic targets, mechanistic antiviral activity, and efficient delivery.

The global pandemic of COVID-19 is a serious public health concern. Over 625 million confirmed cases and more than 6 million deaths have been recorded worldwide. Although several vaccines and antiviral medications have been developed, their efficacy is limited by the emerging new SARS-CoV-2 strains.

Biobutanol production from sustainable biomass process of anaerobic ABE fermentation for industrial applications.

The growing population increases the need to develop advanced biological methods for utilizing renewable and sustainable resources to produce environmentally friendly biofuels. Currently, energy resources are limited for global demand and are constantly depleting and creating environmental problems. Some higher chain alcohols, like butanol and ethanol, processing similar properties to gasoline, can be alternate sources of biofuel.

New insights into cataract surgery in patients with uveitis: A detailed review of the current literature.

Cataract is a common cause of visual impairment in uveitic eyes. The management of cataract in patients with uveitis is often challenging due to pre-existing ocular comorbidities that may limit the visual outcomes. A meticulous preoperative ophthalmic evaluation is needed to assess the concomitant ocular pathologies with special emphasis on the status of the macula and optic nerve.

Application of Gurma Melon Pulp-Based Gel Fat Replacer in Mayonnaise.

Gurma melon pulp-based gel (GMPG) was examined as a fat replacement in mayonnaise. GMPG was used to partially replace fat in quantities of 25, 50, and 70%, abbreviated as GMPG-25, GMPG-50, and GMPG-70, respectively. Mayonnaise's physicochemical and sensory properties were studied.

Preoperative universal screening for COVID-19 in patients undergoing ophthalmic surgeries: Experience from a tertiary eye care center in Saudi Arabia.

Purpose: This study aims to determine the frequency of coronavirus disease-2019 (COVID-19) among patients scheduled for elective and emergency ophthalmic surgeries in a tertiary eye care center in Saudi Arabia.

Methods: This observational retrospective study was performed between June 1, 2020, and October 31, 2020, in a single tertiary eye care center in Riyadh, Saudi Arabia. All patients who were given appointments for elective or emergency surgeries were included in the study.