Nanoparticles: New agents toward treatment of leishmaniasis.

Leishmaniasis is a widespread disease that causes 20,000 to 30,000 deaths annually, making it a major health problem in endemic areas. Because of low-performance medications, drug delivery poses a great challenge for better treatment of leishmaniasis. The present study's purpose was to review the application of nanoparticles as a new method in leishmaniasis treatment To identify all relevant literature, we searched Web of Sciences, Scopus, PubMed, NCBI, Scielo, and Google Scholar, and profiled studies published between 1986 and 2019.

Prophylactic effects of biogenic selenium nanoparticles on acute toxoplasmosis: An in vivo study.

Background: In this investigation, the in vivo efficacy and safety of biogenic selenium nanoparticles (SeNPs) are assessed against acute toxoplasmosis caused by (Sarcocystidae) in the mice.

Methods: Male NMRI mice were orally treated with normal saline (control group) and SeNPs at the doses of 5 and 10 mg/kg once a day for 14 days On the 15th day, the mice were infected with 10 tachyzoites of RH strain by the intraperitoneal route. The mortality rate and parasite load were determined in the infected mice.