Publications by authors named "Esraa AwadAllah"
J Ethnopharmacol
February 2025
Article Synopsis
- Golden berries (Physalis peruviana) are recognized for their neuroprotective qualities and traditional medicinal uses, prompting a study to assess their effectiveness against neurotoxicity caused by cyclophosphamide (CP).
- The study utilized a combination of advanced chromatography and mass spectrometry to analyze the chemical composition of golden berries, alongside behavioral tests and histological evaluations in an animal model to gauge the neuroprotective effects of total leaf extract (TLE).
- Results indicated that TLE significantly preserved hippocampal neurons and enhanced cognitive performance by reducing acetylcholinesterase activity and oxidative stress, while also restoring redox balance through the inhibition of inflammatory pathways.
