Publications by authors named "Esra Tanyel Akcit"

Article Synopsis
  • Tuberculosis, caused by Mycobacterium tuberculosis, is a significant global health issue, and rising drug resistance highlights the urgent need for new treatments.
  • Computer-aided drug design (CADD) is being utilized to create more effective and less toxic drugs for tuberculosis.
  • The study focused on two synthetic peptides, AKVUAM-1 and AKVUAM-2, which were designed to block interactions crucial for M. tuberculosis infection, showing promise without harming normal lung tissue and having varied minimum inhibitory concentrations (MIC) against different bacterial strains.
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Objective: To evaluate the performance of nitrate reductase assay (NRA), a rapid, colorimetric method for the determination of methicillin resistance in Staphylococcus aureus isolates obtained from the culture collection of the Akdeniz University Hospital Central Laboratory, Antalya, Türkiye.

Materials And Methods: Identification for all 290 S aureus isolates at the species level was performed via matrix-assisted laser desorption/ionization-time of flight. Isolates were tested with NRA for methicillin resistance.

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