Moving out of your mind and into your body: Yoga buffers the effects of childhood maltreatment on PTSD symptoms.

Childhood maltreatment has been consistently linked to posttraumatic stress disorder (PTSD) symptoms among college students and yoga may buffer the effects. The current study examined the frequency of college student's yoga practice over the past year as a moderator of childhood maltreatment and PTSD symptoms in the past 30 days. A sample of 177 college students from a southern university.

Expectation-setting and patient education about pain control in the perioperative setting: A qualitative study.

Objective: Interventions aimed at limiting opioid use are widespread. These are most often targeted toward prescribers or health systems. Patients' perspectives are too often absent during the creation of such interventions.

Dyadic parent-adolescent relationship quality as pathways from maternal childhood abuse to adolescent psychopathology.

Children of maternal caregivers abused in childhood are at increased risk for mental health problems including anxiety and depression. To date, most studies exploring the intergenerational transmission of trauma have focused on younger children, with far fewer studies investigating adolescent mental health. Previous research suggests that maternal childhood abuse negatively impacts the parent-adolescent relationship, which may contribute to the development and maintenance of adolescent mental health problems.

Patient Willingness to Accept Antibiotic Side Effects to Reduce Surgical Site Infection After Colorectal Surgery.

Background: Mechanical bowel preparation with antibiotics is associated with decreased surgical site infections (SSI) after colorectal surgery. However, antibiotics have side effects, such as vomiting. It is unknown how patient willingness to take antibiotics is affected by side effect severity.

Home Disposal Kits for Leftover Opioid Medications After Surgery: Do They Work?

Background: Postoperative overprescribing is common, and many patients will have excess medications. An effective method to encourage disposal is lacking. We hypothesized that a convenient home disposal kit will result in more appropriate disposal of excess opioids.

A high amplitude, time reversal acoustic non-contact excitation (trance).

This paper describes the principle behind a high amplitude non-contact acoustic source based on the principle of time reversal (TR), a process to focus energy at a point in space. By doing the TR in an air filled, hollow cavity and using a laser vibrometer in the calibration of the system, a non-contact source may be created. This source is proven to be more energetic than an off the shelf focused ultrasound transducer.

The effects of non-cardioid directivity on incidence angle estimation using the polar energy time curve.

Assessment of desirable reflections and control of undesirable reflections in rooms are best accomplished if the reflecting surfaces are properly localized. Several measurement techniques exist to identify the incident direction of reflected sound, including the useful polar energy time curve (Polar ETC), which requires six cardioid impulse response measurements along the Cartesian axes. The purpose of this investigation is to quantify the incidence angle estimation error introduced into the Polar ETC by non-cardioid microphone directivities.

Retroviral transfer of the glucocerebrosidase gene into CD34+ cells from patients with Gaucher disease: in vivo detection of transduced cells without myeloablation.

Retroviral gene transfer of the glucocerebrosidase gene to hematopoietic progenitor and stem cells has shown promising results in animal models and corrected the enzyme deficiency in cells from Gaucher patients in vitro. Therefore, a clinical protocol was initiated to explore the safety and feasibility of retroviral transduction of peripheral blood (PB) or bone marrow (BM) CD34+ cells with the G1Gc vector. This vector uses the viral LTR promoter to express the human glucocerebrosidase cDNA.

Gaucher disease: recommendations on diagnosis, evaluation, and monitoring.

Background: Timely diagnosis and continued monitoring of patients with type I Gaucher disease is critical because skeletal involvement can permanently disable patients and visceral organ involvement can lead to abdominal pain and secondary hematologic and biochemical complications.

Objective: To seek clinical consensus for minimum recommendations for effective diagnosis and monitoring of patients with type I Gaucher disease. PARTICIPANTS, EVIDENCE, AND CONSENSUS PROCESS: Contributing authors collaborated in quarterly meetings over a 2-year period to synthesize recommendations from peer-reviewed publications and their own medical experiences.

Acceleration of retarded growth in children with Gaucher disease after treatment with alglucerase.

Objectives: The incidence and severity of growth retardation in children with type 1 Gaucher disease and the response to enzyme replacement therapy with alglucerase were studied.

Study Design: A retrospective analysis of growth in 99 children and adolescents with type 1 Gaucher disease before treatment, and in 54 of those subjects during treatment, was done. Growth was compared with gender, age, and dosage of replacement enzyme.

MR imaging of patients with type 1 Gaucher's disease: relationship between bone and visceral changes.

Objective: Because treatment is now available for patients with Gaucher's disease, methods of follow-up have become important in making treatment decisions. Bone abnormalities (infarct and avascular necrosis) tend to be irreversible while visceral volumes are not, suggesting that it may be useful to follow patients with visceral volume determinations. In order to do so, the relationship of one to the other must first be understood.

Phase I/II clinical and pharmacokinetic evaluation of liposomal daunorubicin.

Purpose: Since liposomal encapsulation of anticancer drugs may enhance antitumor activity while reducing toxicity in vitro, we evaluated liposomally encapsulated daunorubucin (DaunoXome; Vestar, Inc, San Dimas, CA) for safety, pharmacokinetics, and potential efficacy in patients with AIDS-related Kaposi's sarcoma (AIDS-KS).

Patients And Methods: Forty patients with advanced AIDS-KS were accrued. Successive cohorts received DaunoXome at doses of 10, 20, 30, and 40 mg/m2 given once every 3 weeks, and 40, 50, and 60 mg/m2 given once every 2 weeks.

All-trans retinoic acid for the treatment of AIDS-related Kaposi's sarcoma: results of a pilot phase II study.

Retinoids have anti-tumor activity in several malignant and premalignant conditions. Since Kaposi's sarcoma is regulated by steroid hormones both in vivo and in vitro, we hypothesized that retinoids may have anti-tumor effects in AIDS-related Kaposi's sarcoma. Thus, 27 patients with mucocutaneous, non-visceral AIDS-related Kaposi's sarcoma were treated with all-trans retinoic acid (tRA).

AIDS-related non-Hodgkin's lymphoma: abdominal CT findings in 112 patients.

Objective: Non-Hodgkin's lymphoma is a common complication in patients with HIV infection. The purpose of this study was to analyze the abdominal CT findings in a large series of patients with this condition.

Materials And Methods: We retrospectively reviewed the abdominal CT examinations of 110 men and two women (21-62 years old; average, 39 years) with untreated AIDS-related lymphoma, as defined by the Centers for Disease Control.