Publications by authors named "Espinosa-Garriga G"
Objectives: Although classification systems and scores for capillaroscopy interpretation have been published, there is a lack of homogenization for the procedure, especially in the way and place the images are taken, the counting of the capillaries and the measuring of their size. Our objective is to provide a deep learning-based software to obtain objective and exhaustive data for the whole nailfold without increasing the time or effort needed to do the examination, or requiring expensive equipment.
Methods: An automated software to count nailfold capillaries has been designed, through an exploratory image dataset of 2,713 images with 18,000 measurements of 3 different types.
Introduction: Our objective was to evaluate the pulmonary hypertension (PH) data for Spanish patients with systemic sclerosis (SSc), define the PH types and determine the associated factors.
Method: Descriptive study of PH-related data from the multicentre RESCLE registry. Estimated systolic pulmonary artery pressure (esPAP), measured via echocardiogram was considered elevated if ≥ 35 mmHg.
Objectives: To evaluate the clinical characteristics of patients with interstitial lung disease (ILD) in the setting of a large cohort of systemic sclerosis (SSc) patients, and to analyse the differences according to the SSc subtype (following the modification of classification criteria of the American College of Rheumatology for SSc proposed by LeRoy and Medsger), factors are associated with moderate-to-severe impairment of lung function, as well as mortality and causes of death.
Methods: A descriptive study was performed, using the available data from the Spanish Scleroderma Study Group.
Results: Twenty-one referral centers participated in the registry.
Article Synopsis
- Systemic sclerosis (SSc) is a rare disease with varying progression and prognosis, and this study analyzed survival rates and mortality causes in 879 Spanish patients.
- Among the patients, 15.7% died, with over half of those deaths attributed to SSc, primarily due to pulmonary hypertension.
- Key factors affecting survival included older age at disease onset, diffuse cutaneous SSc, interstitial lung disease, pulmonary hypertension, and scleroderma renal crisis, which were identified as independent risk factors for mortality.
Objective: To investigate the incidence of clinical and immunological characteristics of a large cohort of Spanish patients with scleroderma (SSc) and identifying factors associated with particular organ manifestations assessed by a nationwide cross-sectional analysis.
Methods: We classified SSc patients in 4 subsets using a modification of LeRoy and Medsger classification that included: "prescleroderma" (pre-SSc), limited cutaneous SSc (lcSSc), diffuse cutaneous SSc (dcSSc), and SSc sine scleroderma (ssSSc). Fourteen Spanish centers participated in patient recruitment.
Background And Objective: To describe the uveitis pattern in our geographic area. Recent demographic, environmental and scientific changes can determine uveitis pattern changes, which we aim to investigate.
Patients And Methods: A cross-sectional study between 1(st) January 2009 and 30(th) June 2010 was done.
The therapeutic goals for a patient with newly diagnosed lupus nephritis should be to achieve a prompt renal remission, to avoid renal flares, to avoid chronic renal impairment, and to fulfil these objectives with minimal toxicity. An advance in the therapy of LN has been the introduction of concepts of induction of remission (by a sort course of vigorous immunosupression such as monthly intravenous cyclophosphamide) and maintenance of remission (by long-term administration of the same cytotoxic drug given less frequently or a potentially safer immunosupressant such as azathioprine). Mycophenolate mofetil may be an alternative to cyclophosphamide for induction and maintenance therapy of patients with proliferative LN.
View Article and Find Full Text PDFIntroduction: Anti-phospholipid antibodies (APA) may involve heart and valvular heart disease seems to be the most common clinical manifestation.
Objectives: To study the prevalence and characteristics of valvular heart disease in a large patient population with anti-phospholipid syndrome (APS) and also to analyze the clinical and immunological profile of patients with valvular involvement compared with those without involvement. Patients and methods.