CMOS-based cryogenic control of silicon quantum circuits.

The most promising quantum algorithms require quantum processors that host millions of quantum bits when targeting practical applications. A key challenge towards large-scale quantum computation is the interconnect complexity. In current solid-state qubit implementations, an important interconnect bottleneck appears between the quantum chip in a dilution refrigerator and the room-temperature electronics.

The impact of low-intensity blood flow restriction endurance training on aerobic capacity, hemodynamics, and arterial stiffness.

Background: The aim of this study was to determine the effects of short-term low-intensity blood flow restriction (BFR) endurance training (ET) programs on measures of aerobic capacity, hemodynamics, and arterial stiffness in healthy young males.

Methods: Thirty-nine healthy young recreationally active males participated in this short-term training study. They were randomly assigned to a high-intensity (HI; N.

Validation of a rational malingering test using evoked potentials.

Malingering is easy to define, difficult to detect, and very costly for any health care system. The structured interview of reported symptoms (SIRS) was constructed using rational strategies to detect malingering in patients endorsing psychotic symptoms. This study validated the SIRS using evoked potentials.

T cell receptor V-segment frequencies in peripheral CD8+ T cells in aging.

Infections are a major cause of illness and death amongst elderly people. Peripheral blood CD8+ T lymphocytes --which play a crucial role in host defence against viral infections--, are divided in subsets based upon the expression of several cell and activation markers. In senescence changes and variations in peripheral CD8+ T lymphocyte compartment have been described, and such a decrease in the CD8+CD45RA+ lymphocytes.

[High- and low-risk molecular sequences in autoimmune diseases. An analysis of type I diabetes in Latin America].

Type I diabetes is an autoimmune and a polygenic disease, in which MHC-class II genes contribute to 48% of the disease. The aim of the present study, is to provide a guideline to understanding the molecular association of these genes, through the immunogenetic analysis of 3 Latin american mestizo populations. We included 606 individuals, 349 patients with DMDI and 257 healthy controls coming from 3 geographical areas: Mexico City, Mexico; Caracas, Venezuela and Medellin, Colombia.

Neutrophil function in elderly persons assessed by flow cytometry.

It is well known that the immune response declines with senescence and it is suggested that these changes render an individual susceptible to infection, autoimmune phenomena and cancer. Bacterial and viral infections are a major cause of illness and death amongst aged subjects, and once infection is established, the elderly also have a diminished capacity to prevent its spread (1). The cellular and molecular basis for this age-related decline in immunocompetence are still unknown and, possibly, are related to an alteration in cell transduction mechanisms (2).

T cell receptor V-segment frequencies in aged individuals.

The T V alpha and V beta cell specificities repertoire usage in aging subjects was studied by the use of seven different monoclonal antibodies specific for defined regions of the T cell receptor (TCR). Except for the V beta 8 subfamily, no differences were observed in the frequency of T cells bearing selected V alpha beta epitopes, between old and control subjects.

CD8+ T cell subsets in aging.

Infections are major cause of illness and death amongst elderly people. Peripheral blood CD8+ T lymphocytes -which play a crucial role in host defence against viral infections-. are divided in subsets based upon the expression of several cell and activation markers.

Distribution of the HLA-DQA1 polymorphism in the population of the Basque Country (Spain).

Allele and genotype frequencies at the HLA-DQA1 locus were determined in Basque Country populations using PCR methodology and a dot-blot assay with ASO probes. The results showed no deviation from the Hardy-Weinberg equilibrium. No differences were found between the three Basque Provinces, but gene frequencies were significantly different from those of some other Spanish and world populations.

HTLV-I/II infections in Spain. The HTLV-I/II Spanish Study Group.

Antibodies to HTLV-I/II were investigated in sera from 7521 individuals living in Spain. They were classified in four major groups: a) subjects at high risk of retroviral infections e.g.

Epidemiology and inmunogenetics in recently diagnosed Venezuelan children with insulin-dependent diabetes mellitus.

Genetic and immunological markers in children with Type I diabetes have not been studied previously in Venezuela. We evaluated 91 newly diagnosed IDDM children mean age 7.8 +/- 4.

[Human immunodeficiency virus infection in the Spanish population. Review of the literature].

The epidemiological aspects of the infection by the human immunodeficiency virus, HIV, in the Spanish population as described in the literature are reviewed. From the published studies is evident that HIV infection is limited to the population risk groups established in the epidemiological world reports, heroin addicts, homosexuals, heterosexuals with sexual contacts with infected persons and blood and hemoderivates receptors. The observed frequencies in these risk groups are similar to that described in other countries.

[Epidemiologic aspects of acquired immunodeficiency syndrome (AIDS). Review].

A revision of the World current epidemiological aspects of the acquired immunodeficiency syndrome is presented. It was observed that near 70% of all the world cases occurred in the United States of America and 12% in Europe. There is an increase tendency of the number of cases.

[Diseases in heroin addiction].

An analysis of the medical pathologies seen in heroin addicts heroin addicts hospitalized in the Provincia de Vizcaya, Basque Country, Spain, from 1982 to 1987, and its possible association to the infection by the human immunodeficiency virus, HIV, is presented. An increasing of hospitalized addicts per year was observed, being infectious diseases the main pathology detected. HIV infection was present in more than 90% of individuals with non opportunistic acquired infections.

[Human immunodeficiency virus (HIV) infection in País Vasco, Spain].

An analysis of the epidemiology of the human immunodeficiency virus infection in the Basque Country, Spain is presented. The infection by this virus is mainly detected in intravenous drug addicts. In homosexuals the seropositivity frequency detected was moderate, and infection was also detected in sexual partners of drug addicts.

Antibodies to acquired immune deficiency syndrome (AIDS)-associated virus (HTLV-III/LAV) in Venezuelan populations.

Serum samples from 850 individuals from Venezuela were tested for the presence of antibodies to HTLV-III/LAV virus, the probable etiological agent of acquired immune deficiency syndrome (AIDS). At the time of the study, none of the individuals tested had symptoms indicative of AIDS or related disorders. Viral antibodies were assayed by indirect immunofluorescence (IF) assay, using a chronically infected, HTLV-III/LAV producer cell line CEM/LAV-NIT established in our laboratory.

Antibodies to AIDS-associated retrovirus (HTLV-III/LAV) in drug addicts from Vizcaya, northern Spain.

Serum samples from 313 asymptomatic intravenous (IV) drug users from Bilbao (Vizcaya, Vasque Country, Spain) were tested for antibodies to HTLV-III/LAV virus, the probable etiologic agent of the acquired immune deficiency syndrome (AIDS). Viral antibodies were assayed by ELISA test. 41.