Adjunctive use of modified Yunu-Jian in the non-surgical treatment of male smokers with chronic periodontitis: a randomized double-blind, placebo-controlled clinical trial.

Background: Yunu-Jian (YJ) is a Chinese medicine (CM) heat purging formula, which is used to reduce wei huo (stomach-heat, SH) and enrich shen yin (kidney-yin, KY). This formula is also commonly used to manage diabetes mellitus and gum/oral inflammation. The activity of YJ can be modified or refined by the addition of other CM herbs and/or minor changes to one of its five key ingredients.

Impact of dentine hypersensitivity on oral health-related quality of life in individuals receiving supportive periodontal care.

Aim: To determine the prevalence and impact of dentine hypersensitivity (DH) on oral health-related quality of life (OHRQoL) in individuals receiving supportive periodontal care (SPC).

Materials And Methods: One hundred and two adults receiving SPC were recruited for a cross-sectional study. Subjects were categorized into those who self-reported DH (DH1) or did not (DH0).

Survival of molar teeth after resective periodontal therapy--a retrospective study.

Aim: To study outcomes of molar teeth after resective therapy performed with the intention to prolong the lifespan of teeth having one or more unsaveable roots, and without which tooth extraction would be inevitable.

Material And Methods: Clinical records of 149 subjects who had undergone resective therapy were retrieved. Demography and dental history were recorded, and a recall examination was undertaken.

Non-surgical periodontal therapy improves oral health-related quality of life.

Aim: The influence of non-surgical periodontal therapy on oral health-related quality of life (OHQoL) was investigated.

Materials And Methods: Sixty-five Chinese adults (25 men, mean 47.4 years) with moderate-to-advanced chronic periodontitis were recruited.

Graduates' perceived preparedness for dental practice from PBL and traditional curricula.

The objective of this study was to compare dental graduates' perceived preparedness for practice after being educated in a problem-based learning (PBL) curriculum with those who graduated from a traditional undergraduate curriculum, both at the University of Hong Kong. A cohort of graduates from the traditional dental curriculum (1997-2001) and a cohort of graduates from the PBL curriculum (2004-08) rated their self-perceived preparedness for dental practice in fifty-nine aspects of dentistry across nine domains. Perceived preparedness for dental practice was compared at domain and item levels (accounting for multiple comparisons) using chi-square statistics.

Periodontal conditions in elderly men with and without osteoporosis or osteopenia.

Background: The purpose of this case-control study is to investigate the periodontal conditions in elderly men with and without osteoporosis or osteopenia and to determine their possible association with periodontal destruction.

Methods: A total of 200 community-dwelling Chinese males (age range: 69 to 78 years; mean ± SD age: 71.9 ± 3.

Effects of smoking on healing response to non-surgical periodontal therapy: a multilevel modelling analysis.

Aim: To investigate the factors predicting non-surgical periodontal treatment responses using multilevel multiple regression.

Material And Methods: Forty men (mean 45.6 years) were recruited; 20 were smokers.

Toll-like receptors 2 and 4 gene polymorphisms in a Chinese population with periodontitis.

Objectives: Polymorphisms for toll-like receptor (TLR) 2 gene (Arg677Trp, Arg753Gln) and TLR4 gene (Asp299Gly, Thr399Ile) that are associated with impaired lipopolysaccharide (LPS) signal transduction have recently been described. The present study aimed to investigate the relationship between TLRs 2 and 4 gene polymorphisms and periodontitis in a Chinese population.

Method And Materials: Forty patients with generalized aggressive periodontitis, 50 patients with chronic periodontitis, and 100 periodontally healthy controls were recruited.

Health behaviour, metabolic control and periodontal status in medically treated Chinese with type 2 diabetes mellitus.

Objective: Relationships between demographic, health behaviour and diabetes mellitus (DM) parameters and periodontal status were assessed among a group of nonsmoking, low-income, middle-aged to elderly medically treated Hong Kong Chinese subjects with type 2 diabetes mellitus (DM).

Materials And Methods: 193 Chinese, dentate, type 2 DM patients (56.5 +/- 9.

Non-surgical periodontal therapy with adjunctive chlorhexidine use in adults with down syndrome: a prospective case series.

Background: Subjects with Down syndrome (DS) experience a high prevalence of periodontal disease, and the management of this disease in subjects with DS is a challenge for oral health care providers. The purpose of this case series was to follow the periodontal healing response changes over a 12-month period after non-surgical mechanical periodontal therapy with the adjunctive use of chlorhexidine and monthly recalls in adults with DS who presented initially with chronic periodontitis.

Methods: Twenty-one subjects with DS (14 males and seven females; 25.

Oral health status of adults with Down syndrome in Hong Kong.

The aim of this survey was to study the oral health status of Hong Kong Chinese adults with Down syndrome (DS). Sixty-five community-dwelling adults with DS (aged 17 to 42 years, 26.8+/-6.

Periodontal diseases in Asians.

Asia encompasses three of the four most populous nations in the world (China, India and Indonesia), accounting for nearly two-fifths of the worlds' total population. Over half of the world's population now inhabits Asia, which by definition includes countries of the Middle East and some former Socialist Soviet Republics. There has been a generally held view that Asians are particularly susceptible to periodontitis.

Repeated oral hygiene instructions alone, or in combination with metronidazole dental gel with or without subgingival scaling in adult periodontitis patients: a one-year clinical study.

The aims of the present study were to evaluate the clinical efficacy of, and to monitor microbiologically, repeated oral hygiene instructions alone or in combination with metronidazole 25% gel or subgingival scaling with or without metronidazole gel in treatment of new, residual or recurrent periodontal pockets in previously treated adult periodontitis patients. Ten suitable patients were included in this randomized single-blind clinical study with an intra-individual design. Clinical parameters were measured before and at 1, 3, 6, 9 and 12 months after treatment.

Tooth loss in treated periodontitis patients responsible for their supportive care arrangements.

Aim: To identify risk indicators associated with tooth loss and periodontitis in treated patients responsible for arranging supportive periodontal care (SPC).

Materials And Methods: Ninety-seven Chinese subjects (34-77 years) who showed favourable responses to periodontal therapy provided in a teaching hospital 5-12 years previously were recalled. They were advised to seek regular SPC on discharge.

Association of matrix metalloproteinase-1 promoter polymorphism with generalized aggressive periodontitis in a Chinese population.

Background: A single nucleotide polymorphism in the promoter region of -1607 bp of the human matrix metalloproteinase-1 (MMP-1) gene has been found to be associated with an increased risk of various inflammatory diseases and cancer metastasis.

Objectives: The present study aimed to examine the distribution of MMP-1 genotypes in a group of Chinese subjects with generalized aggressive periodontitis and a group of periodontally healthy subjects, and to evaluate the possible association of the MMP-1 promoter polymorphism with aggressive periodontitis.

Methods: Genomic DNA was obtained from whole blood samples in 40 Chinese subjects with generalized aggressive periodontitis and 52 periodontally healthy subjects as controls.

A regimen of systematic periodontal care after removal of impacted mandibular third molars manages periodontal pockets associated with the mandibular second molars.

Aim: This randomized, single-blinded control trial investigated the local effects of periodontal care on the mandibular second molar delivered during and after impacted third molar surgical extraction.

Method: Thirty subjects (50% male, 32.1+/-7.

Characterization of Actinobacillus actinomycetemcomitans isolated from young Chinese aggressive periodontitis patients.

Objective: This study characterized Actinobacillus actinomycetemcomitans isolates from young Chinese aggressive periodontitis patients.

Methods: Subgingival plaque samples (two/subject) were collected from diseased subjects < 25 years old (n = 9, mean age 21.1 +/- 1.

Microflora cultivable from minocycline strips placed in persisting periodontal pockets.

Objective: The microflora that develops on minocycline strips, used as an adjunct in non-surgical periodontal therapy was studied.

Design And Methods: Minocycline (1.4 mg in polycaprolactone vehicle) and control strips were applied into all residual pockets (PD > or = 5mm, > or =2 pockets/subject) of patients with chronic periodontitis 1 month after a course of non-surgical periodontal therapy.

Clinical responses to mechanical periodontal treatment in Chinese chronic periodontitis patients with and without Actinobacillus actinomycetemcomitans.

Background: The purpose of this study was to compare 12-month clinical responses to mechanical periodontal treatment in Chinese chronic periodontitis patients at sites with and without Actinobacillus actinomycetemcomitans at baseline, and to investigate the ability of mechanical periodontal treatment to eliminate A. actinomycetemcomitans.

Methods: Nineteen patients and a total of 76 selected sites with a mean probing depth (PD) of > or = 7 mm were studied.

Granulocyte elastase activity in static and flow gingival crevicular fluid.

Objectives: This study aimed to evaluate the volume of gingival crevicular fluid (GCF) and granulocyte elastase activity in static GCF (sGCF) and flow GCF (fGCF) from subjects with various periodontal conditions.

Methods: Eleven periodontally healthy, 10 gingivitis and 12 periodontitis subjects were recruited and the sites investigated consisted of healthy sites from healthy subjects (HH); healthy (HG) and gingivitis sites (GG) from gingivitis subjects; and healthy (HP), gingivitis (GP) and periodontitis sites (PP) from periodontitis subjects. fGCF samples were collected either 1 min or 5 min following sGCF collection by paper strip technique.