Publications by authors named "Esmeralda Rios Sanchez"
Article Synopsis
- Many patients do not respond completely to biologic drugs like infliximab, adalimumab, or etanercept, and the effectiveness of these drugs can decrease over time, prompting the need for better monitoring techniques.
- A study was conducted using patient data to analyze levels of these drugs and their corresponding anti-drug antibodies, revealing a significant link between lower drug levels and treatment failure, particularly in psoriasis cases.
- The researchers proposed new therapeutic ranges for these drugs that are lower than current standards, which could enhance the ability to predict treatment success and call for more studies to validate these findings.
Objective: Ustekinumab is used in moderate-severe plaque psoriasis with inadequate response to anti-tumour necrosis factor α drugs. Recent studies support the need to assess real long-term data. The aim of this study was to evaluate the real long-term effectiveness and safety of ustekinumab in moderate-severe plaque psoriasis refractory to 2 anti-tumour necrosis factor α drugs.
View Article and Find Full Text PDFThe objective of this article is to analyze the ratio of cost-effectiveness and budgetary impact of lenalidomide treatment in patients with multiple myeloma who have undergone autologous transplant in Spain. The analyses were based on clinical trials CALGB 100104 and IFM 2005-02, from the perspective of the National Health System. The alternatives compared were the treatment with lenalidomide against maintenance without treatment (MwT).
View Article and Find Full Text PDFWhat Is Known And Objective: Rheumatoid arthritis (RA) is an autoimmune disease characterized primarily by inflammation and pain in the joints. Tofacitinib is an oral drug recently approved for RA treatment; it inhibits Janus protein kinases (JAK) that reduces RA symptoms when conventional DMARDs do not trigger a response. This study aimed to compare the efficacy of biological DMARDs in monotherapy or combined with methotrexate in RA patients and compare the treatments.
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