Publications by authors named "Esmee Verburgt"
Article Synopsis
- A study aimed to compare ischemic stroke incidence rates between rural and urban areas in the Netherlands, focusing on younger adults (15-49 years) and older adults (50+ years).
- Researchers analyzed hospital data from 1998 to 2018, examining 23,720 younger patients and 369,107 older patients, and categorized municipalities based on urbanization and socioeconomic status.
- Results showed that younger adults in rural areas had a 5% higher risk of ischemic stroke compared to those in urban settings, while older adults had a 3% lower risk, highlighting significant age-specific disparities in stroke incidence.
Background: Patent foramen ovale (PFO) is a congenital anatomical variant which is associated with strokes in young adults. Contrary to vascular risk factors and atherosclerosis, a PFO is present from birth. However, it is completely unknown how an anatomical structure that is already present at birth in a large proportion of the population can convert into a PFO that causes stroke in a few.
View Article and Find Full Text PDFImportance: Cause of ischemic stroke in young people is highly variable; however, the risk of recurrence is often presented with all subtypes of stroke grouped together in classification systems such as the Trial of ORG (danaparoid sodium [Orgaran]) 10172 in Acute Stroke Treatment (TOAST) criteria, which limits the ability to individually inform young patients with stroke about their risk of recurrence.
Objective: To determine the short-term and long-term risk of recurrent vascular events after ischemic stroke at a young age by stroke cause and to identify factors associated with recurrence.
Design, Setting, And Participants: This cohort study used data from the Observational Dutch Young Symptomatic Stroke Study, a prospective, multicenter, hospital-based cohort study, conducted at 17 hospitals in the Netherlands between 2013 and 2021.
Background: Small hyperintense lesions are found on diffusion-weighted imaging (DWI) in patients with sporadic small vessel disease (SVD). Their exact role in SVD progression remains unclear due to their asymptomatic and transient nature. The main objective is to investigate the role of DWI+lesions in the radiological progression of SVD and their relationship with clinical outcomes.
View Article and Find Full Text PDFArticle Synopsis
- * The study involves 50 participants who will temporarily stop their antihypertensive medication to observe changes in blood pressure and its impact on brain health using various MRI techniques and clinical assessments.
- * Findings from the study aim to shed light on how hypertension might lead to SVD, potentially leading to new treatment strategies to prevent or slow down this disease in the future.