Background: Stress associated with changes in host immunity occurs in response to altered environmental conditions, endogenous imbalances, infectious agents and harmful stimuli. The importance of genetic diversity in chickens has increased due to individual immune differences towards resistance and susceptibility to various stimuli.
Objectives: This study aimed to investigate the association of major histocompatibility complex (MHC) polymorphism with acute phase response (APR) in Ross 308 broiler chickens.
Pharmacol Res Perspect
August 2024
Contrast-induced nephropathy (CIN) is a serious complication that occurs subsequent to the administration of contrast media for therapeutic angiographic interventions. As of present, no effective therapy exists to prevent its occurrence. This single-center double-blind randomized controlled trial aimed to evaluate the effect of edaravone, an antioxidant, in a group of high-risk patients undergoing coronary angiography.
View Article and Find Full Text PDFBackground: Major histocompatibility complex (MHC) is the best characterised genetic region associated with adaptive immune responses, including humoral and cell-mediated immunities.
Objectives: In this study, the association of MHC class II alleles with inflammatory cytokines and acute-phase proteins was evaluated in sheep population.
Methods: Allelic diversity of second exon of ovine DRB1 locus (Ovar-DRB1.
Background: Maedi-Visna (MV) is a progressive lymphoproliferative viral disease that affects multiple organs of small ruminants, including sheep and goats. The disease occurs primarily in the lung tissue and causes interstitial pneumonia.
Aims: The aim of present study was to investigate the prevalence of ovine MV infection in Iranian sheep population through macroscopic, histopathological, serological, and molecular assays, as well as transmission electron microscopy (TEM).
Backgrounds: The development of a canine-specific method of immunocontraception is one of the non-invasive controlling strategies for humanely decreasing the dog population. This study was aimed to investigate the potential of whole sperm in stimulating the immune system and producing specific anti-sperm antibodies (ASAs) in female dogs. Mature, mixed-breed bitches were subcutaneously immunized with high (200 × 10 cells/mL) and low (100 × 10 cells/mL) doses of sperm vaccine, emulsified with Freund's adjuvants.
View Article and Find Full Text PDFBACKGROUND Hepatic dysfunction has been associated with poor prognosis in critically ill patients. We aimed to investigate the incidence of early liver dysfunction and its association with probable predictive variables in a group of Iranian patients. METHODS The study was conducted on 149 pediatric patients referred to the pediatric intensive care unit (PICU), Shiraz University of Medical Sciences, Shiraz, Iran between April and October 2016.
View Article and Find Full Text PDFBackground: Villegas-Glisson/University of Georgia (VG/GA) strain of Newcastle disease virus (NDV) is recommended for the initial vaccination of commercially reared turkey poults. However, the vaccine-induced antibody responses have not been studied in this species. The level of systemic humoral immune responses against the NDV was investigated in commercial turkey poults vaccinated with the VG/GA vaccine.
View Article and Find Full Text PDFObjectives: To find the relationship between Helicobacter pylori infection and iron deficiency anemia in school-aged children.
Methods: 71 children with dyspepsia, epigastric and vague abdominal pain attending a tertiary medical center in Iran underwent upper gastrointestinal endoscopy and were investigated for H. Pylori infection.
Salmonella species have been the major foodborne problems in food production systems, with Salmonella enterica serovars typhimurium (S. typhimurium) and enteritidis (S. enteritidis) being among the more common isolates.
View Article and Find Full Text PDFBackground: Association between Chronic Hepatitis C virus (CHC) infection and type 2 diabetes mellitus has been challenging in recent decades. Despite of extensive research in this area, there is no general agreement on the direct effect of HCV infection on insulin resistance.
Patients And Methods: The study was performed in 52 CHC patients (mean age = 39.
Major histocompatibility complex (MHC) has a profound influence on disease resistance or susceptibility, productivity and important economic traits in chicken. Association of the MHC with a wide range of immune responses makes it a valuable predictive factor for the disease pathogenesis and outcome. The tandem repeat LEI0258 is a genetic marker which is located within the B locus of chicken MHC and strongly associated with serologically defined haplotypes.
View Article and Find Full Text PDFBackground: Inflammatory bowel diseases (IBDs), including ulcerative colitis (UC) and Crohn's disease (CD), are chronic inflammatory disorders of the gastrointestinal tract. A combination of environmental factors and interactions with a genetic predisposition are suggested to play an important role in the etiology and pathogenesis of the IBD. Glutathione S-transferases (GSTs) are multifunctional enzymes involved in the cellular oxidative stress handling.
View Article and Find Full Text PDFMajor histocompatibility complex (MHC) is the best-characterized genetic region associated with resistance and susceptibility to a wide range of diseases. In cattle, the most important example of the relationship between the MHC and infectious diseases has been established by the resistance to Bovine leukemia virus (BLV) infection. The association of the bovine MHC class II BoLA-DRB3.
View Article and Find Full Text PDFBackground: This study investigated the in vitro and in vivo antibacterial effects of three mouthwashes on supragingival plaque microbiota. The three mouthwashes under study were 0.2% chlorhexidine (CHX), Listerine®, and Persica (PM).
View Article and Find Full Text PDFMajor histocompatibility complex (MHC) is the best characterized genetic region controlling disease resistance and immune responses in chicken. MHC genes are also involved in various non-immune functions such as productive traits and reproductive success. The genetic diversity of MHC in an Iranian indigenous chicken (Khorasan) was studied, and association of the MHC alleles with production traits was determined.
View Article and Find Full Text PDFMicrosatellite LEI0258 is a genetic marker for chicken MHC haplotypes and can be used as an indicator of the influence of population genetics on immune responses. LEI0258 microsatellite variability in three Iranian indigenous chicken populations (Khorasan, Marandi, and Arian) was investigated. In total, 142 Khorasan, 42 Marandi, and 58 Arian chickens were examined.
View Article and Find Full Text PDFLittle is known about asymmetry of children's dental arches. The purposes of this study were to quantify and describe dental arch asymmetry of 151 children with large overjets, and to determine if a spatial relationship exists between dental landmarks in opposing arches. The median palatal plane (MPP) was the reference for transverse measurements.
View Article and Find Full Text PDFTo determine whether the positions of the palatal rugae were affected by orthodontic therapy, pre- and posttreatment maxillary dental casts of 57 adult patients treated in the graduate orthodontic clinic at the University of North Carolina were evaluated. The orthodontic extraction group (n = 27) was composed of patients whose treatment included the extraction of two maxillary premolars. The remaining patients (n = 30) had been treated without extractions.
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