Power-Modified Kies-Exponential Distribution: Properties, Classical and Bayesian Inference with an Application to Engineering Data.

We introduce here a new distribution called the power-modified Kies-exponential (PMKE) distribution and derive some of its mathematical properties. Its hazard function can be bathtub-shaped, increasing, or decreasing. Its parameters are estimated by seven classical methods.

Multicolor diagnosis of salivary alkaline phosphatase triggered by silver-coated gold nanobipyramids.

Alkaline phosphatase (ALP) is one of the most versatile biomarkers for early detection of several diseases, such as oral carcinomas and periodontitis; therefore, great efforts have been dedicated for developing an ALP biosensor. Multicolor detection of ALP in saliva is ideal for a point-of-care diagnosis; however, this approach is very challenging since spectral responses over wavelengths of several tens of nanometers have thus far remained difficult to achieve. In this work, a colorimetric biosensor for ALP assay has been developed based on ALP affinity to dephosphorylate glucose phosphate into glucose, which has the affinity to deposit Ag nanoshells onto Au nanobipyramids with a multicolor response.