Do prognosis and clinicopathological features differ in young early-stage breast cancer?

Background: Breast cancer is the most frequently detected cancer and the leading cause of cancer-related death in women. Although it is mostly seen in older patients, breast cancer affects women aged 24 to >70 years, with poorer prognosis in young patients. Young age remains a controversial topic in the literature.

Assessment of Optical Coherence Tomography Findings in Adults with Attention Deficit Hyperactivity Disorder: A Case-Control Study.

Background: To assess retinal nerve fiber layer and ganglion cell-inner plexiform layer thickness using optical coherence tomography in attention deficit hyperactivity disorder adults on regular methylphenidate treatment, comparing them to healthy controls.

Methods: A total of 33 attention deficit hyperactivity disorder adults and 31 healthy subjects, matched for age, gender, and education (control group), were included in this study. Retinal nerve fiber layer and ganglion cell-inner plexiform layer thickness of both eyes were measured using optical coherence tomography, and symptom severity was evaluated using Adult Attention Deficit Hyperactivity Disorder Self-Report Scale and Wender Utah Rating Scale.

Adverse events report of inactivated COVID-19 vaccine from 4040 healthcare workers.

Objectives: Numerous vaccination studies are conducted to protect against COVID-19 infection, and preclinical and clinical studies are still ongoing worldwide. During this extraordinary period, the necessity to perform COVID-19 vaccine studies and immunization programs together has emerged. Vaccine Adverse Effects (VAEs) need to be documented quickly.

The Impact of the Informed Consent Process on the Anxiety Levels of Patients Undergoing Rhinoplasty.

Septorhinoplasty is one of the most common elective surgical procedures in otolaryngology. The present study aimed to evaluate the anxiety levels of patients who underwent septorhinoplasty at different times, compare the information methods, and determine the understanding of the informed consent through recall rates of the complications explained in the informed consent process. The patients were divided into the following 2 groups: Group 1 (giving information 14 days before the surgery) and Group 2 (giving information 3 days before the surgery).

Clarifying the relationship between sarcopenia and depression in geriatric outpatients.

Objective: We investigate the relationship between sarcopenia components and depression in geriatric outpatients, considering the effects of potential confounding factors.

Methods: Adults ≥60 years of age were selected from outpatient clinics. Muscle strength was assessed using handgrip strength (HGS) measured using a hydraulic hand dynamometer and chair stand test (CSST).

Effects of a psychoeducation program on disease burden, depression, and anxiety levels in relatives of psychotic patients in a community mental health center.

Purpose: This study evaluates the effect of a 10-week psychoeducation program (PP) on disease burden, depression, and anxiety levels in relatives of psychotic patients.

Design And Methods: The participants were 43 relatives of patients attending a community mental health center. The Zarit Caregiver Burden Scale (ZCBS), Beck Anxiety Inventory (BAI), and Beck Depression Inventory (BDI) were used to collect psychometric data.

Impulsivity, Sensation Seeking, and Decision-Making in Long-Term Abstinent Cannabis Dependent Patients.

Introduction: In contrast to several studies that examined different domains of neurocognitive functions in long-term abstinent cannabis users, there are few studies examined impulsivity in cannabis users with prolonged abstinence. The aim of this study was to test whether impulsivity and sensation seeking traits and impulsive decision-making are transient or enduring in patients with cannabis dependence who were abstinent for at least 1 month.

Methods: The study included 30 patients with cannabis dependence (CDP) who had been abstinent for at least 1 month and 30 healthy controls.

Effect of humic deposit (leonardite) on degradation of semi-volatile and heavy hydrocarbons and soil quality in crude-oil-contaminated soil.

In order to investigate the bioremedial potential of humic deposit (leonardite), the effects of the treatments of leonardite and a commercial bioaugmentation agent on the degradation of a variety of petroleum hydrocarbons (C13-C31) and soil enzyme activities (urease acid-alkaline phosphatase and dehydrogenase) were tested within a soil incubation experiment lasting 120 days. Experimentally crude-oil-contaminated soil (2.5%) was regulated to a C:N:P ratio (100:15:1; Oilcon), amended with 5% of leonardite and regulated to the same C:N:P ratio (Oilcon-L) or mixed with a commercial bioaugmentation product (Oilcon-B), respectively.

The effects of heavy metal pollution on enzyme activities and basal soil respiration of roadside soils.

In this study, soil samples (0-5 cm depth) were taken from ten different roadside fields of intensive traffic regions of Van-Turkey in order to determine the effects of heavy metal pollution on enzymes and microbial activities of soils. Basal soil respiration (BSR), arylsulphatase (ASA), alkaline phosphatase (APA) and urease (UA) enzyme activities, and heavy metal contents (Pb, Cr, Ni, Cd, Fe, Mn, Cu and Zn) of soils significantly changed with 5, 25 and 45 m from the roadside of soil sampling positions. BSR, ASA, APA and UA activities significantly increased while the heavy metal contents generally decreased from the sampling position of 5 m through 25 and 45 m.

Delirium and extrapyramidal symptoms due to a lithium-olanzapine combination therapy: a case report.

We report an elderly patient who developed severe delirium and extrapyramidal signs after initiation of lithium-olanzapine combination. On hospital admission, serum levels of lithium were found to be 3.0 mM/L which were far above toxic level.