Publications by authors named "Esienanwan E Efiong"
Phenolic acid-rich fraction from Anisopus mannii (PhAM) contains abundance of ferulic acid, gallic acid, protocatechuic acid, and syringic acid. Among other glycolytic enzymes, in vitro, PhAM counteracted the binding of sodium orthovanadate to phosphofructokinase 1 (PFK-1), improving its activities. In a rat model of diet-induced diabetes, PhAM monotherapy reduced HbA1c by an average of 0.
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- Diabetic kidney disease (DKD) is the leading cause of kidney failure, often progressing to end-stage renal disease (ESRD), and is mainly managed through strict blood glucose and blood pressure control.
- The complexities and mechanisms behind DKD are not well understood, hindering the development of effective treatments despite ongoing research.
- This review summarizes recent studies exploring the relationship between high blood sugar, oxidative stress, and cellular dysfunction that contribute to DKD, emphasizing the need for better understanding to create new treatment options.
Glutathione, glutathione peroxidase and some hematological parameters of HIV-seropositive subjects attending clinic in University of Calabar teaching hospital, Calabar, Nigeria.
BMC Infect Dis
November 2019
Background: Despite the numerous intervention programmes, HIV still remains a public health concern with a high impact in Sub-Saharan Africa region. Oxidative stress has been documented in HIV subjects as viral infection promotes prolonged activation of immune system, hence, production of increased reactive oxygen species.
Methods: We studied 180 subjects.
Background: Low concentration of trace elements has been associated with poor prognosis and mortality in HIV infection.
Methods: A cross sectional study was conducted among 100 HIV-infected subjects (70 were on ART treatment, while 30 were ART naïve). Fifty (50) apparently healthy controls were enrolled.