Publications by authors named "Eshed I"

Objectives: This study aims to establish expert consensus recommendations for clinical information on imaging requests in suspected/known axial spondyloarthritis (axSpA), focusing on enhancing diagnostic clarity and patient care through guidelines.

Materials And Methods: A specialised task force was formed, comprising 7 radiologists, 11 rheumatologists from the Assessment of Spondyloarthritis International Society (ASAS) and a patient representative. Using the Delphi method, two rounds of surveys were conducted among ASAS members.

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Article Synopsis
  • The text discusses a correction to a previously published article indexed under the DOI 10.3389/fgene.2022.987867.* -
  • The correction aims to address specific inaccuracies or errors found in the original study.* -
  • This update is important for maintaining the integrity of the research and ensuring accurate scientific communication.*
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Background: A range of sacroiliac joint (SIJ) MRI protocols are used in clinical practice but not all were specifically designed for diagnostic ascertainment. This can be confusing and no standard diagnostic SIJ MRI protocol is currently accepted worldwide.

Objective: To develop a standardised MRI image acquisition protocol (IAP) for diagnostic ascertainment of sacroiliitis.

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Purpose: Assess whether a Retroaortic left renal vein (RLRV) affects vertebral osteophyte formation in the lumbar spine, compared to normal anatomy left renal vein.

Methods: We conducted a retrospective case-control study. Computed tomography (CT) scans of individuals with a RLRV (study group) were compared to age- and gender-matched normal anatomy CT scans (control group).

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Whereas previous projects attempted to standardize imaging in patients with axial spondyloarthritis (axSpA), few studies have been published about the need for specific details regarding the image acquisition and lesions that may be less familiar to general radiologists. This work reports consensus recommendations developed by the Assessment of SpondyloArthritis International Society (ASAS) that aim to standardize the imaging reports in patients suspected of having or with known axSpA. A task force consisting of radiologists and rheumatologists from ASAS and one patient representative formulated two surveys that were completed by ASAS members.

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Palliative radiation is often used to abate pain and prevent bone fractures in patients with metastatic cancer. Hypofractionation, meaning delivery of larger doses of radiation in each treatment session (fraction), has become the standard of care in most cases. It not only reduces the burden on the medical system and facilitates the relief of symptoms but also enables the maintenance of the continuity of systemic therapy.

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Background: Traumatic knee injuries are challenging to diagnose accurately through radiography and to a lesser extent, through CT, with fractures sometimes overlooked. Ancillary signs like joint effusion or lipo-hemarthrosis are indicative of fractures, suggesting the need for further imaging. Artificial Intelligence (AI) can automate image analysis, improving diagnostic accuracy and help prioritizing clinically important X-ray or CT studies.

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Sacroiliitis is commonly seen in patients with axial spondyloarthritis, in whom timely diagnosis and treatment are crucial to prevent irreversible structural damage. Imaging has a prominent place in the diagnostic process and several new imaging techniques have been examined for this purpose. We present a summary of updated evidence-based practice recommendations for imaging of sacroiliitis.

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Article Synopsis
  • Reliable interpretation of imaging findings is crucial for diagnosing axial spondyloarthritis (axSpA), and this study explored how experience level affects diagnostic accuracy using X-ray (XR), MRI, and CT.
  • The study analyzed 163 low back pain patients, dividing nine blinded readers into three experience groups to assess their ability to identify axSpA through imaging.
  • Results indicated that the most experienced readers performed best overall, especially with MRI, while CT and MRI were more effective for less experienced readers, highlighting that MRI requires more skill and experience for accurate diagnosis.
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Background: The Spondyloarthritis Research Consortium of Canada (SPARCC) developers have created web-based calibration modules for the SPARCC MRI sacroiliac joint (SIJ) scoring methods. We aimed to test the impact of applying these e-modules on the feasibility and reliability of these methods.

Methods: The SPARCC-SIJ e-modules contain cases with baseline and follow-up scans and an online scoring interface.

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Objective: To develop a reference image atlas for scoring the hip/pelvis region according to the OMERACT whole-body MRI scoring system for inflammation in peripheral joints and entheses (MRI-WIPE).

Methods: We collected image examples of each pathology, location and grade, discussed them at web-based, interactive meetings and, finally, selected reference images by consensus.

Results: Reference images for each grade and location of osteitis, synovitis and soft tissue inflammation are provided, as are definitions, reader rules and recommended MRI-sequences.

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Objective: To develop a reference image atlas for the Outcome Measures in Rheumatology whole-body MRI scoring system for inflammation in peripheral joints and entheses (OMERACT MRI-WIPE) of the knee region.

Methods: Image examples of each pathology, location and grade, were collected and discussed at web-based, interactive meetings within the OMERACT MRI in Arthritis Working Group. Subsequently, reference images were selected by consensus.

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Objective: Assess the diagnostic utility of repeat sacroiliac joint (SIJ) magnetic resonance imaging (MRI) examinations following an inconclusive initial examination performed for suspected sacroiliitis.

Method: Subjects with > 1 SIJ MRI examinations, an inconclusive first scan and at least 6 months interval between scans, were included. All scans were evaluated for the presence of structural/active SIJ lesions as well as any other pathology.

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Objectives: Scaphoid fractures are usually diagnosed using X-rays, a low-sensitivity modality. Artificial intelligence (AI) using Convolutional Neural Networks (CNNs) has been explored for diagnosing scaphoid fractures in X-rays. The aim of this systematic review and meta-analysis is to evaluate the use of AI for detecting scaphoid fractures on X-rays and analyze its accuracy and usefulness.

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Article Synopsis
  • The study investigates how sex-specific differences affect the diagnosis of axial spondyloarthritis (axSpA) in women compared to men, which may lead to delays in diagnosis.
  • A total of 526 patients were analyzed for MRI findings related to axSpA, focusing on lesions like bone marrow edema and fat metaplasia.
  • Results showed that while active inflammatory lesions had similar diagnostic performance in both sexes, structural markers were less reliable in women, increasing the chances of false positives.
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  • The study aimed to assess how self-reported diagnostic confidence (DC) correlates with diagnostic accuracy in imaging for axial spondyloarthritis (axSpA) using X-rays, CT, and MRI.
  • Results showed that higher DC scores corresponded with accurate axSpA diagnoses across all imaging modalities, indicating a significant difference in scores for correct versus incorrect assessments.
  • The findings support the inclusion of self-reported DC in radiological reports to enhance the reliability of diagnoses in axSpA imaging.
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Background: Bone marrow lesions (BMLs) and synovitis on magnetic resonance imaging (MRI) are associated with symptoms and predict degeneration of articular cartilage in osteoarthritis (OA). Validated methods for their semiquantitative assessment on MRI are available, but they all have similar scoring designs and questionable sensitivity to change. New scoring methods with completely different designs need to be developed and compared to existing methods.

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Autonomous finite element analyses (AFE) based on CT scans predict the biomechanical response of femurs during stance and sidewise fall positions. We combine AFE with patient data via a machine learning (ML) algorithm to predict the risk of hip fracture. An opportunistic retrospective clinical study of CT scans is presented, aimed at developing a ML algorithm with AFE for hip fracture risk assessment in type 2 diabetic mellitus (T2DM) and non-T2DM patients.

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Background: Following first-time lateral patellar dislocation (FTLPD), most patients are treated conservatively, although 50% of patients will have recurrent dislocations. Typically, radiographs followed by CT and/or MRI are used to assist the clinician in determining treatment strategy and, combined with clinical findings, intraarticular free bodies (CT/MRI), significant medial patellofemoral ligament (MPFL) tear (MRI) and lateral displacement of the patella (CT) form relative indications for surgery.

Methods: Radiographs, MRI and CT knee studies of 34 patients after lateral patellar dislocation (26 FTLPD) were evaluated for intraarticular free bodies, patellar/trochlear fracture, lateral femoral condyle compression, MPFL tear, tibial tuberosity-trochlear groove (TT-TG) distance, and surgery indications.

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Diffuse idiopathic skeletal hyperostosis (DISH) is a systemic condition characterized by new bone formation and enthesopathies of the axial and peripheral skeleton. The pathogenesis of DISH is not well understood, and it is currently considered a non-inflammatory condition with an underlying metabolic derangement. Currently, DISH diagnosis relies on the Resnick and Niwayama criteria, which encompass end-stage disease with an already ankylotic spine.

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Objective: Transient Osteoporosis of the Hip is a self-limiting disorder of severe hip joint pain presenting in pregnancy or postpartum, of which magnetic resonance imaging (MRI) is the modality of choice for diagnosis. Clinical data regarding transient osteoporosis of the hip is limited, precluding evidence-based decision-making such as recommended mode of delivery. In this case-series retrospective study, we aim to describe the natural course of transient osteoporosis of the hip during pregnancy and the postpartum period including implications of the mode of delivery.

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  • Pelvic radiography is often the first imaging test recommended for diagnosing axial spondyloarthritis (axSpA), but its effectiveness in identifying sacroiliitis is limited compared to CT and MRI.
  • Recent findings indicate that low-dose CT is more sensitive than traditional radiographs, and MRI is preferred for early detection of sacroiliac joint inflammation.
  • The debate is ongoing about the relevance of pelvic radiographs, as newer imaging techniques like low-dose CT and advanced MRI provide more accurate diagnoses for sacroiliitis.
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Aims: To evaluate structural changes of costovertebral joints (CVJ) in patients with radiographic axial spondyloarthritis (rAxSpA) using computed tomography (CT) studies.

Methods: Available chest or thoracic spine CT studies of 17 patients with rAxSpA and 17 patients with rheumatoid arthritis (RA) were analyzed. Ankylosis, erosions, joint space narrowing, and osteophytes were assessed.

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Objective: To assess the prevalence and clinical relevance of quadratus femoris muscle edema (QFME) in pediatric pelvic MRI.

Materials And Methods: The axial T2-W with fat saturation sequence of pelvic/hip MRI examinations of pediatric patients (≤ 18 years) and a control group of young adults aged 19-45 years was retrospectively and independently evaluated by two musculoskeletal radiologists for the presence of QFME in each hip. Demographics, indication for imaging studies, and pain location were documented.

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