Morphometric parameters of dental pulp in immature teeth in a sheep model after mechanical pulp exposure and restoration with reinforced zinc oxide-eugenol.

Background: The aim of the study was to investigate the morphometric parameters of dental pulp in open apices immature teeth in a sheep model after mechanical pulp exposure and restoration with reinforced zinc oxide-eugenol.

Materials And Methods: In this experimental study, a total of 12 immature mandibular central incisors from six adult male sheep, weighing 30-40 kg and with the age of 1 year old with Merino race were examined. After anesthesia, the pulps of the teeth in the case group were mechanically exposed and then were restored with reinforced zinc oxide-eugenol and amalgam.

Scanning electron microscopic evaluation of the effect of different root-end resection methods in the crack formation in root canals filled with mineral trioxide aggregate or calcium-enriched mixture cement.

Background: There is some concern that root resection may alter the surface features and crack formation of the previously set orthograde material. The aim of this study was to evaluate the crack formation in orthograde mineral trioxide aggregate (MTA) and calcium-enriched mixture (CEM) plugs after root resection.

Materials And Methods: This study was conducted on 170 extracted human maxillary anterior teeth.

Outcomes of root canal therapy or full pulpotomy using two endodontic biomaterials in mature permanent teeth: a randomized controlled trial.

Objective: The concept of minimally invasive endodontics recommends less-invasive vital pulp therapy (VPT) modalities over more aggressive traditional endodontic approaches in mature permanent teeth with carious pulp exposure, including irreversible pulpitis (IP) cases. Consequently, VPT needs to be compared with root canal therapy (RCT) in terms of treatment outcomes. This randomized clinical trial compares the results of full pulpotomy using two calcium-silicate cements, i.

Postendodontic Pain after Pulpotomy or Root Canal Treatment in Mature Teeth with Carious Pulp Exposure: A Multicenter Randomized Controlled Trial.

This equivalence, randomized, clinical trial aimed to compare the postoperative pain of root canal therapy (RCT) with pulpotomy with mineral trioxide aggregate (PMTA) or calcium-enriched mixture (PCEM) in permanent mature teeth. In seven academic centers, 550 cariously exposed pulps were included and randomly allocated into PMTA ( = 188), PCEM ( = 194), or RCT ( = 168) arms. Preoperative "Pain Intensity" (PI) on Numerical Rating Scale and postoperative PIs until day 7 were recorded.

Proliferation, odontogenic/osteogenic differentiation, and cytokine production by human stem cells of the apical papilla induced by biomaterials: a comparative study.

Introduction: Clinical applications of bioactive materials are increasing in biomedical tissue engineering. This study sought to assess the effect of calcium enriched mixture (CEM) cement, Biodentine, mineral trioxide aggregate (MTA), octacalcium phosphate (OCP), and Atlantik on proliferation, odontogenic/osteogenic differentiation, and pro-inflammatory cytokine production by human stem cells of the apical papilla (SCAPs).

Materials And Methods: Proliferation of SCAPs treated with different biomaterials was evaluated using trypan blue exclusion test and flow cytometry.

Bilateral Presence of Two Distobuccal Canals in Maxillary First Molars: A Case Report.

This article describes the diagnosis and treatment of bilaterally maxillary first molars with two canals in their distobuccal roots. A 13-year-old male came to the clinic with a severe pain of tooth #14. In the first session, after access and finding the main canals and the second mesio-buccal (MB2) canal, another canal was noticed in the distobuccal root.

Interaction of intracanal medicaments with apical papilla stem cells: quantitative cytotoxicity assessment by methyl thiazolyl tetrazolium, trypan blue and lactate dehydrogenase.

Background: Chemical residues often have cytotoxic effects on the stem cells. This study aimed to assess the cytotoxic effects of intracanal medicaments on stem cells of the apical papilla (SCAPs) using methyl thiazolyl tetrazolium (MTT), trypan blue exclusion (TBE) and lactate dehydrogenase release (LDHR) assays.

Methods: SCAPs were cultured and exposed to 0.

Endodontic Treatment of a Maxillary Lateral Incisor with Two Canals: A Case Report.

Variations in the number of roots and canals have been extensively reported in endodontic literature. One rare variation is presence of two separate root canals in maxillary lateral incisors. This study reports a maxillary lateral incisor with two canals.

Computed tomography evaluation of root canal transportation using ProTaper, Race and Sendoline rotary systems: an ex vivo study.

Background: This ex vivo study aimed to compare transportation of the mesiobuccal root canal of mandibular first molars instrumented with ProTaper, Race and Sendoline rotary systems using cone beam computed tomography (CBCT).

Materials And Methods: Forty-five mesiobuccal canals of mandibular first molars were randomly divided into three groups of 15. Root canals in each group were instrumented with the ProTaper, Race or Sendoline rotary system according to the manufacturers' instructions.

Comparative Evaluation of Root Canal Transportation by Three NiTi Single-File Systems in Curved Canals: A Cone Beam Computed Tomography Study.

Introduction: This study is aimed at evaluating root canal transportation in the mesiobuccal canal of mandibular first molars prepared with One Shape, Reciproc, and M-One nickel titanium (NiTi) single-file rotary systems using cone beam computed tomography (CBCT).

Materials And Methods: In this ex vivo study, CBCT scans of 45 extracted human mandibular first molars with 20-40° curvature were obtained. The teeth were randomly divided into three groups (=15) for preparation of the mesiobuccal canal with One Shape, Reciproc, and M-One rotary systems according to the manufacturers' instructions.

Apical Extrusion of Intracanal Bacteria with Single File and Multifile Rotary Instrumentation Systems.

Aims And Objectives: Instrumentation techniques may cause extrusion of microorganisms and their products into the periapical region resulting inflammation and treatment failure. The aim of this study was comparing the apical bacterial extrusion in canals prepared with single file versus multiple file rotary systems.

Materials And Methods: Ninety-two human single-rooted mandibular first premolars were used.

Value of CBCT in vertical root fracture detection in endodontically-treated teeth.

Background: Vertical root fracture (VRF) is a diagnostic challenge for dentists. Cone-beam computed tomography (CBCT) scans provide accurate three-dimensional images of teeth enabling detection of VRFs. This in-vivo study compared the accuracy of CBCT and exploratory surgery for detection of VRFs in endodontically-treated teeth.

Evaluation of Cytotoxic Effects of Various Endodontic Irrigation Solutions on the Survival of Stem Cell of Human Apical Papilla.

Introduction: Root canal disinfection is an important step in regenerative endodontic treatments. An ideal irrigating solution must have high antimicrobial activity and minimum cytotoxicity. This study sought to assess the effect of some irrigating solutions on stem cells from the human apical papilla (SCAP) after different periods of exposure.

Detection of Carious Lesions and Restorations Using Particle Swarm Optimization Algorithm.

Background/Purpose. In terms of the detection of tooth diagnosis, no intelligent detection has been done up till now. Dentists just look at images and then they can detect the diagnosis position in tooth based on their experiences.

In-vitro evaluation of coronal microbial leakage after post space tooth preparation.

Background: The aim of this in-vitro study was to determine the occurrence of coronal microbial leakage in endodontically treated teeth that have been prepared for post space, and also determine the minimum and maximum time required for the permanent restoration of the teeth after post space preparation.

Methods: This experimental study was conducted using a simple random sampling. Fifty extracted single-root teeth with approximately the same length were selected for this study.

Analysis of methylation and mRNA expression status of FADD and FAS genes in patients with oral squamous cell carcinoma.

Background: Apoptosis is an important mechanism that is responsible for the physiological deletion of harmful, damaged, or unwanted cells. Changed expression of apoptosis-related genes may lead to abnormal cell proliferation and finally to tumor genesis. Our aims were to analyze the promoter methylation and gene expression profiles of FADD and FAS genes in risk of OSCC.

Evaluation of the effect of blood contamination on the compressive strength of MTA modified with hydration accelerators.

Objectives: This study was performed to evaluate the effect of blood contamination on the compressive strength (CS) of Root MTA (RMTA) modified with Calcium chloride (CaCl2) and Disodium hydrogen phosphate (Na2HPO4) as setting accelerators over time.

Materials And Methods: A total of 110 cylindrical specimens of RMTA were divided into 6 experimental groups as follows: Group1, RMTA; Group 2, RMTA modified with CaCl2 (RMTA-C); Group 3, RMTA modified with Na2HPO4 (RMTA-N); Group 4, RMTA contaminated with blood; Group 5, RMTA-C contaminated with blood; Group 6, RMTA-N contaminated with blood. The CS of specimens in all groups was evaluated after 3 hr, 24 hr, and 1 wk.