Knowledge and perceptions about fragile X syndrome and fragile X-premutation-associated conditions among medical doctors in Nigeria.

Fragile X syndrome (FXS) is a significant cause of intellectual disability and autism, while Fragile X Premutation -Associated Conditions (FXPAC) are a significant cause of morbidity and mortality globally. This study assessed the level of knowledge and perceptions about FXS and FXPAC among doctors in Nigeria. It was a web-based, cross-sectional study conducted among a cohort of doctors in Nigeria.

Malaria Diagnosis at the Pediatric Emergency Unit of a Teaching Hospital in Makurdi, North Central Nigeria.

Background: Globally, there were 241 million cases of malaria in 2020, with an estimated 627,000 deaths with Nigeria accounting for 27% of the global malaria cases. In sub-Saharan Africa, testing is low with only 28% of children with a fever receiving medical advice or a rapid diagnostic test in 2021. In Nigeria, there are documented reports of over-diagnosis and over-treatment of malaria in children.

Burden of COVID-19 Pandemic on Adolescents' Quality of Life: A Cross-Sectional Study among Secondary School Students in North-Central Nigeria.

Background: The Coronavirus disease 2019 (COVID-19) has caused millions of mortalities globally. Although the prevalence and fatality rates of COVID-19 among adolescents is low, its impact on their health-related quality of life (HRQoL) is not adequately known. This study was carried out to determine the burden COVID-19 pandemic has on the HRQoL of adolescents.

Human Monkey Pox Virus Infection in Plateau State, North Central Nigeria: A Report of Two Cases.

Background: Human Monkey Pox Virus (HMPV) infection is a zoonotic infection that is endemic in the Congo basin and West Africa. Its similarity to smallpox infection, increased susceptibility infection in human populations, lack of a definitive therapy and its potential for use as a bioterrorism tool underscores its public health importance.

Objective: To describe the characteristics of HMPV infection in Plateau State, North Central Nigeria.

Knowledge, Attitude and Practice on Covid-19 among Clinical Healthcare Workers in Bingham University Teaching Hospital (BHUTH) Jos, Plateau State, Nigeria.

Background: The ongoing Covid-19 pandemic is now a global health emergency with significant morbidity and mortality among different populations of the world. Healthcare professionals are the people in the front line of situations like this. Their perspectives on the pandemic is critical to their safety and the outcomes in patients they manage.

Facility-Based Surveillance Activities for COVID-19 Infection and Outcomes among Healthcare Workers in a Nigerian Tertiary Hospital.

COVID-19 in healthcare workers (HCWs) can result in nosocomial transmission, depletion in available workforce, and enhanced community transmission. This article describes surveillance for COVID-19 in HCWs at a tertiary healthcare facility, and documents the outcomes. A descriptive cross-sectional study of all HCWs identified from surveillance for COVID-19 from March 31 to August 31, 2020 was conducted.

Management and Outcome of a Case of Osteogenesis Imperfecta in Benue State University Teaching Hospital, Makurdi, North-Central Nigeria.

Osteogenesis Imperfecta is a genetic disorder of the connective tissue leading to generalised osteoporosis, fragility of the skeletal system and susceptibility to fractures of the long bones and compression of the vertebrae from mild or inconsequential trauma. It is one of the rare diseases known to mankind. It has no definitive cure and treatment is essentially supportive.

Risk Factors Associated with Adolescent Obesity in an Urban Area, North-West Nigeria.

Background: Adolescence is a vulnerable period of transition and a time for establishing healthy or risky behaviours. Adolescents constitute the strategic link between a nation's past and the future. Adolescent obesity is an epidemic of global proportions which has affected both industrialized and developing countries.

Impact of Epilepsy on Adolescents in a Rural Nigerian Community: A Case-Control Study.

Background: Epilepsy is associated with impaired physical, psychological and social functioning. Assessing its impact on these parameters is important to improving the wellbeing of those with the disorder.

Objective: To assess the impact of epilepsy on the physical, psychological and social status of adolescents in a rural community.

Strong family history and early onset of schizophrenia: about 2 families in Northern Nigeria.

Schizophrenia is a highly heritable psychotic disorder and high genetic loading is associated with early onset of the disease. The outcome of schizophrenia has also been linked with the age of onset as well as the presence of family history of the disease. Therefore families with patients with early onset Schizophrenia are subpopulations for genetic studies.

Descriptive Characterization of Psycho-Trauma, Psychological Distress, and Post-traumatic Stress Disorder among Children and Adolescent Internally Displaced Persons in Kaduna, Nigeria.

Background: A postelection violent conflict in Kaduna resulted in 800 deaths and 65,000 displaced people leading to setting up of camp for internally displaced persons (IDPs). We set out to determine the prevalence and pattern of psycho-traumatic stressful life events, psychological distress, and post-traumatic stress disorder (PTSD) among child/adolescents IDPs.

Methods: A descriptive cross-sectional study of 73 child/adolescent IDPs were selected by total sampling.

Knowledge of Childhood Autism and Challenges of Management among Medical Doctors in Kaduna State, Northwest Nigeria.

Autism is a neurodevelopmental disorder with serious implications in childhood. There is a significant gap in the identification and provision of health and social services for autism in Africa. The knowledge of autism among health care providers and identifying challenges associated with its management could facilitate bridging the gap and ensuring better outcomes.

Childhood epilepsy in a tropical child psychiatric unit: challenges of providing care in a resource-constrained environment.

Background: Epilepsy is an important cause of childhood morbidity and its care is fraught with challenges. Itinerant search for remedy and manifestation as or with psychiatric disorders could result in presentation in a psychiatric unit. Identification of these challenges is essential to providing optimal care.

Natal tooth and cultural impact on its management in a tropical neonatal unit: a case report.

The incidence of natal tooth is uncommon and its management could be fraught with challenges. A 3 day old female presented with features of sepsis and a natal tooth. Treatment for sepsis was permitted and successfully instituted but definitive management of the natal tooth was deferred, for cultural reasons, by the parents.

Challenges in care of the child with special health care needs in a resource limited environment.

To identify challenges encountered in the care of children with special health care needs in a resource limited environment a 10 year-old child with a diagnosis of Tuberous Sclerosis was studied. Challenges identified were in: making a definitive diagnosis, provision of adequate care, cost of care, meeting parental expectations and accessing community support for the child and family. Available specialist health care and related services, including community rehabilitation, were provided for the child and family.

A comparative assessment of motor function using the expanded and revised gross motor function classification system and the manual ability classification system in the same children with cerebral palsy in Shika, Zaria, Northwestern Nigeria.

Background: Assessment of motor function in children with Cerebral Palsy (CP) is vital to the identification and management of their mobility needs.

Objective: To compare the Expanded and Revised Gross Motor Function Classification System (GMFCS-E&R) and Manual Ability Classification System (MACS) in the assessment of motor function in children with CP.

Methods: A review of motor activity in children with CP documented at the Departments of Paediatrics and Physiotherapy, Ahmadu Bello University Teaching Hospital, Shika, Zaria, between January 2005 and December 2009.

Febrile seizures in Kaduna, north western Nigeria.

Background: Febrile seizure is the most common seizure of childhood and has a good prognosis. However its presentation is fraught with poor management, with grave consequences, in our environment. Thus a review of its current status is important.

Health Care Seeking Behavior among Caregivers of Sick Children Who Had Cerebral Malaria in Northwestern Nigeria.

Cerebral malaria is a significant cause of childhood morbidity in our region. The challenges of effective management include time and quality of treatment. The study appraised the health care seeking behavior of caregivers of sick children who developed cerebral malaria, in Zaria, northwestern Nigeria.

Diagnosing renal failure due to diethylene glycol in children in a resource-constrained setting.

Background: In 2008, several Nigerian children developed acute kidney injury (AKI) after ingesting teething syrup contaminated with diethylene glycol (DEG). Because there are limited diagnostic facilities in resource-constrained countries, this study investigated whether AKI associated with DEG could be identified by other means.

Methods: This was a multicenter study.

Patent medicine sellers: how can they help control childhood malaria?

Roll Back Malaria Initiative encourages participation of private health providers in malaria control because mothers seek care for sick children from them. This study investigated Patent Medicine Sellers (PMS) management of presumptive malaria in children in order to identify how they can assist malaria control. A cross-sectional survey of 491 PMS in Kaduna, Nigeria, was done using interviews and observation of shop activities.

Computerized tomography of children with seizure disorders.

Background: Neuro-imaging is generally considered as part of the evaluation of seizures and epilepsy. There is limited information about its usefulness in our environment. We describe the pattern of CT findings in children with seizures in our environment.

Triplet gestation: clinical outcome of 14 cases.

Background/objective: To determine maternal complications and fetal outcome of triplet gestations.

Method: Retrospective study of pregnant women with triplet gestation managed in 10 years.

Results: Fourteen women were managed with triplet gestation, of these, (71.