[Effect of anthropo-technogenic load on medico-social aspects of primary morbidity and disability of population.].

Population aging is a global social phenomenon that affects the most important health indicators of the population. The older generation is particularly vulnerable in the current conditions of urbanization and the associated environmental situation. The comprehension of indicators of disability and morbidity of the population, the study of the factors that determine the negative processes of health damage, taking into account regional features of these processes are necessary for the planning of preventive measures.

[The Post-Operative Complications as an Evaluation Indicator of Efficiency of Functioning of Three-Level System of Medical Care Support According to Urology Profile in the Voronezh Oblast].

In the Voronezh Oblast, the modernization of system of medical care support of patients with urological pathology was implemented with the purpose of increasing efficiency of the urological service functioning. This action affected all levels: early active detection of urological pathology, standardization of examination and treatment, routing of patients, strict control by way of monthly reports of medical institutions of the Oblast at the level of hospital and out-patient services, supervisory visits of specialists to districts and efficient control on part of the Oblast Chief Out-of-Staff Urologist. In the course of study it is established that key indices characterizing efficiency of functioning of the regional system of urological care of population are admitted the levels of unreasonably prolonged conservative treatment and also reasonably application of low invasive and high-tech intervention, implementation of standardization of the curative diagnostic process, rate of post-operative complications, level of economic costs of diagnostic and treatment, level of medical competence of personnel and degree of early detection of urological pathology that is validated by statistically reliable positive effect at the expense of their adjustment.

[The Indices of Common and Early Detection of Urological Pathology as Criteria of Efficiency of Urological Care Rendering].

The comparative statistical and logical analysis of curves of dynamics of common and early detection of urological pathology was implemented with purpose of evaluating efficiency of functioning of regional urological service in the format of developed three-level system of medical care as exemplified by the Voronezh oblast. The obtained statistical data testify a significant increasing of common detection and detection at early stages of urolithiasis, benign hyperplasia and prostate cancer. This outcome is an evidence of partial or complete realization of transition from model of medical care by appealability to model by detection at the expense of implementation of developed three-level system of medical care of population in the region.

[Gerontology and geriatric service in Voronezh region: from the origin into the future.].

The article concerns demographic situation in Voronezh region. The authors have analyzed morbidity and mortality from various diseases in senior age groups. Geriatric service quality in Voronezh region has been estimated.

[Gingerbreads of enhanced nutritional value with the non-traditional raw materials].

The results of the research on quality indicators and nutritional value of gingerbreads made from non-traditional raw materials are presented. The flour from whole-hulled chickpea seeds, whole-wheat flour, flour from the buckwheat bran and mustard oil has been used. Non-traditional types of flour were added in the form of flour composite mixture instead of wheat flour (50%) according to the recipe of glazed gingerbread, mustard oil - 8% to the total weight flour.

[Characteristics of Voronezh schoolchildren physical development and nutrition behavior].

Physical development and nutrition behavior of schoolchildren in Voronezh depending on their age were studied. Research included 484 children aged 8-17: 236 (48.8%) girls and 248 (51.

Evaluation of work conditions and transitory disablement morbidity among paramedical personnel.

The studies revealed that work of paramedical personnel can be assigned to 2 jeopardy class in chemical factor, noise, vibration, illumination, work hardiness; in unfavorable parameters of microclimate in summer period and work intensity - to 3.1 class, in biologic factor - to 3.1-3.

Occupational risks in occupational morbidity structure and possibilities to reduce them.

The article presents results of occupational morbidity analysis in a region, with assessment of trends, levels, dynamics and structure of morbidity, factor dependency of occupational diseases, identification of occupational conditions of its occurrence. The information obtained helped to specify a system of occupational risk management, that increases efficiency in solving problems and better work safety in production.

[TYPE 2 DIABETES MELLITUS AND DEPRESSION].

The clinical significance of type 2 diabetes mellitus is not confined to metabolic disorders. A serious problem is also affective pathology that occurs in the majority (30-70%) of patients. However, diagnostics and correction of anxiety and depressive disorders associated with diabetes are often given insufficient attention.

[Anemias in chronic obstructive pulmonary disease].

According to different studies, anemia occurs in 8--33% of patients with chronic obstructive pulmonary disease (COPD). The paper describes the most important various causes of anemia in COPD, such as systemic inflammation and endocrine disorders, the use of some medications (theophylline, angiotensin-converting enzyme inhibitors), frequent COPD exacerbations, and long-term oxygen therapy. Lower hemoglobin levels in COPD patients are accompanied by increased shortness of breath, reduced exercise tolerance, and lower quality of life.

[ANEMIC SYNDROME IN PATIENTS WITH COMMUNITY-ACQUIRED PNEUMONIA].

Community-acquired pneumonia remains a most widespread acute infectious disease of socio-economic significance all over the world. Up to 30% of the patients present with anemia responsible for the unfavourable prognosis and elevated mortality. Not infrequently, anemia is not diagnosed during the hospital stay und therefore remains uncorrected.

[Differential diagnostics of febrile conditions in an emergency care clinic].

We undertook the analysis of 157 cases of fever at the stages of polyclinic - admission department - hospital treatment for the purpose of elucidating the structure of febrile syndrome. Pneumonia developed in 45 patients, infectious endocarditis in 34, chronic alcoholic hepatitis in 21, rheumatoid arthritis (pseudoseptic variant) in 2, systemic lupus erythematosus in 1, polymyositis in 2, acute pyelonephritis (exacerbation of chronic pyelonephritis) in 15, tumours of different localization in 37 patients. We evaluated the informative value of some acute-phase blood characteristics obtained, results of X-ray and ultrasonic studies for early diagnostics of pneumonia and infectious endocarditis.

[STUDY OF THE IMPACT OF WHEAT GERM CAKE OIL AND FLOUR ON INDICES OF ENERGY EXCHANGE IN STUDENTS AND TEACHERS OF HIGH SCHOOL].

There were obtained data which confirm the increase of efficiency of gas exchange processes in students and teachers of the engineering high school in the daily use of at least 3.5 g of wheat germ oil and 50 g of wheat germ cake flour without the correction of the basic ration. The study of the exhaled gas-air mixture showed in all age groups the gain in the concentration of carbon dioxide and the decline of concentration of oxygen by the 0.

Selected cyclic citrullinated peptides derived from the sequence of mutated and citrullinated vimentin (MCV) are targeted by different antibodies subclasses in patients with rheumatoid arthritis in Russian patients.

Objectives: Antibodies against citrullinated antigens (ACPA) represent one rheumatoid arthritis (RA) classification criteria. Recently, mutated and citrullinated vimentin (MCV), containing approx. 45 potentially citrullinated sites, was characterised as another modified autoantigenic RA target.

[Application of extremely high frequency (EHF) therapy as a method of complex therapy of the elderly patients with mixed form of bronchial asthma].

The effectiveness assessment of using EHF-acupuncture to prevent the attacks in the patients of mixed forms of bronchial asthma is given. The article presents the special scheme of treatment of patients of different age groups in different phase of the disease using the points of acupuncture with the application of EHF.

[Oxidative stress in the pathogenesis of stroke].

Free radical oxidation of lipids and proteins is the universal process constantly proceeding in cells, tissues and organs during the lifetime of organism. In certain conditions, this process can be a basis of pathology, one of the mechanisms of disease development, including stroke.

[Effectiveness of laser puncture in elderly patients with bronchial asthma accompanied by chronic rhinosinusitis].

We apply laser puncture to influence biological active points with infra red laser ionizing at scheme with effect of treatment of asthma bronchial with chronic accompanied by rhino sinusitis. The clinical effectiveness of treatment was seen in positive dynamics of clinical, instrumental and spirographycal indices regarding bronchial asthma and concomitant rhinitis as well, which was confirmed by X-ray examination. Application of laser punctureto treat the elderly patients with asthma bronchial accompanied by rhino sinusitis is an effective method having no side effects that can be used in an ambulatory and in a hospital.

Oxidant stress in the pathogenesis of multiple sclerosis.

We report here an analysis of measures of the intensification of lipid peroxidation and the state of the non-enzymatic and enzymatic components of the antioxidant defense system in different clinical forms and stages of multiple sclerosis. The data obtained support the role of oxidant stress in the development of the pathological process in multiple sclerosis.

[Oxidant stress in the pathogenesis of multiple sclerosis].

The problem of pathogenesis of multiple sclerosis is of great importance in modern neurology and its solution allows to determine a pathogenetic approach to treatment of this severe disease. Parameters of intensification of lipid peroxidation and indices of the state of enzymatic and non-enzymatic patterns in antioxidant defense system in different clinical forms and at different stages of MS course have been analyzed. The data obtained confirm the presence of oxidant stress in the development of pathological process in MS.

[Experience in the elaboration of a program of public health development with medical insurance for an industrial region].

Requirements in medical care and availability of such care for the population of an industrial regions with the towns of Staryĭ Oskol and Gubkin is analyzed. The authors emphasize the unique type of the region. Approaches to improvement of the level of public health in this region at the expense of coordination of the activities of medical and public health institutions, equipment of therapeutic and prophylactic institutions with modern therapeutic and diagnostic devices, and upgrading the knowledge and skills of physicians and paramedical personnel, which may be implemented by professors and teachers of the N.