Effects of acute creatine supplementation on cardiac and vascular responses in older men; a randomized controlled trial.

Background And Aims: In the recent years creatine has been shown promising results in patients with neurodegenerative diseases, myopathies and dystrophies. Cardiovascular diseases could be another pathology that can benefit from creatine supplementation, considering the influence on the risk factors associated with the development of cardiovascular diseases including reduction in chronic inflammation, and improved control of hyperglycemia and dyslipidemia The aim of the present study was to investigate the impact of short-term creatine supplementation on cardiac and vascular health in older adults.

Methods: Males between the ages of 55-80 were randomly assigned to three groups: creatine, placebo and control.