Purpose: Sclerostin inhibits bone formation and stimulates bone resorption. Previous studies found a positive association between bone density and serum sclerostin, but literature on sclerostin levels in osteoporotic fracture patients is scarce. The aim of the present study was to compare the serum sclerostin levels in osteoporotic and non-osteoporotic fracture patients and to assess the correlation of the sclerostin levels with bone mineral density and vitamin D status.
View Article and Find Full Text PDFJ Clin Res Pediatr Endocrinol
December 2016
Objective: Although vitamin D levels are not routinely monitored in pediatric fracture patients, identification of children with a vitamin D deficiency may be clinically relevant because of the potential role of vitamin D in fracture healing. This study aimed to determine the prevalence of vitamin D deficiency in a pediatric fracture population and to identify risk factors for deficiency.
Methods: All pediatric patients (<18 years) who were treated for a fracture of the upper or lower extremity from September 2012 to October 2013 in the outpatient setting of a level one trauma center were included in this cross-sectional study.
Introduction: Vitamin D is essential for bone mineralization and for the subsequent maintenance of bone quality. Mineralization is part of hard callus formation and bone remodelling, processes, which are part of fracture healing. We provide a comprehensive review of the literature to summarize and clarify if possible, the cellular effects of vitamin D and its clinical involvement in the process of fracture healing in human.
View Article and Find Full Text PDFNed Tijdschr Geneeskd
July 2012
Background: Spontaneous haemopneumothorax is a rare disorder and is defined as spontaneous pneumothorax associated with the accumulation of more than 400 ml of blood in the pleural cavity.
Case Description: A 32-year-old male presented at the emergency department following sudden onset of right-sided stinging chest pain and difficulty in breathing. The chest X-ray showed right-sided hydropneumothorax.