Changes in hematopoietic stem cell numbers following acute exercise in non-athlete marathon runners.

Purpose: Hematopoietic stem cell (HSC) transplant is one of the curative methods for some patients with hematological malignancies. Granulocyte colony-stimulating factor (G-CSF) is the most common drug used to mobilize CD34 cells, generally found in small numbers. Recent evidence showed that exercise causes transient mobilization in HSC.

The relationship between cardiac damage biomarkers and heart rate variability following 60 min of running.

Purpose: Endurance exercise may cause transient alterations in cardiac tissue. The number of studies evaluating the relationship between changes in heart rate variability (HRV) and cardiac biomarkers following an endurance event is limited. We hypothesized that there would be a time-dependent correlation between biomarkers of cardiac damage and the reduction in parasympathetic indices of HRV within 24 h after 60 min of running in middle-aged recreational runners.