Acute decompensated heart failure (ADHF) presents a significant clinical challenge characterized by frequent hospitalizations, high mortality rates, and substantial healthcare costs. The united index of hemoglobin, albumin, lymphocytes and platelets (HALP) is a new indicator that reflects systemic inflammation and nutritional status. This study aimed to investigate the prognostic utility of the HALP score and hematological parameters in predicting short-term mortality among ADHF patients admitted to the coronary care unit (CCU).
View Article and Find Full Text PDFThis paper proposes a novel targeted blend of machine learning (ML) based approaches for controlling wastewater treatment plant (WWTP) operation by predicting distributions of key effluent parameters of a biological nutrient removal (BNR) process. Two years of data were collected from Plajyolu wastewater treatment plant in Kocaeli, Türkiye and the effluent parameters were predicted using six machine learning algorithms to compare their performances. Based on mean absolute percentage error (MAPE) metric only, support vector regression machine (SVRM) with linear kernel method showed a good agreement for COD and BOD, with the MAPE values of about 9% and 0.
View Article and Find Full Text PDFBackground: Heart failure (HF) causes high morbidity and mortality worldwide. The prevalence of HF with preserved ejection fraction (HFpEF) is increasing compared with HF with reduced ejection fraction (HFrEF). Patients with HFpEF are a patient group with a high rate of hospitalization despite medical treatment.
View Article and Find Full Text PDFInt J Environ Res Public Health
September 2022
COVID-19-related school closures caused unprecedented and prolonged disruption to daily life, education, and social and physical activities. This disruption in the life course affected the well-being of students from different age groups. This study proposed analyzing student well-being and determining the most influential factors that affected student well-being during the COVID-19 pandemic.
View Article and Find Full Text PDFEpilepsy is a neurologic condition that is occurs globally and is associated with various degrees of seizures. Levetiracetam is an approved drug that is commonly used to treat seizures in juvenile epileptic patients. Accurate quantification of the drug's active compound and determining its stability in the stomach after oral administration are important tasks that must be performed.
View Article and Find Full Text PDFThe Allium genus vegetables are of special interest since being potentially sources for selenium. In this study, the metabolization of selenite and selenate fortification at low and high levels in hydroponically cultivated Allium porrum (Leek) was investigated. The total Se analysis of nutritional solutions which was used in cultivation medium revealed that leeks had potential to accumulate Se above over 1000 mg/kg without any growth disturbance which was proved by comparing dry masses of control group with the ones fortified by Se species.
View Article and Find Full Text PDFβ-thalassemia major is a significant health problem in the world that obliges patient to repeated blood transfusions. Frequent transfusions cause toxic iron overload and the association between serum iron levels and β-thalassemia major have been extensively studied in literature. Nonetheless, data on trace elements is still limited.
View Article and Find Full Text PDFBackground: In this study, the effectiveness of intraventricular (IVT) antibiotic administration was evaluated in the treatment of ventriculo-peritoneal (VP) shunt infection by comparing patients who received only systemic antibiotic treatment with patients who received antibiotics added to systemic therapy by IVT route.
Methods: From July 2009 to July 2019, 78 shunt infection episodes of 74 pediatric patients with bacterial growth in cerebrospinal fluid (CSF) culture who were treated with the diagnosis of VP shunt infection were retrospectively analyzed. The demographic data, clinical and laboratory parameters, antimicrobial management, and treatment outcomes of patients with VP shunt infections were recorded.
Thalassemia major is the most severe form of thalassemia and occurs with the impaired synthesis of β-globin which causes the accumulation of unpaired alpha globin chain. Patients with beta thalassemia major can only survive with periodically safe blood transfusions leading to the accumulation of iron in the bloods of patients, and this causes several endocrinopathies. Although iron overload in thalassemic patients has been extensively studied, there is little information about the levels of other trace elements.
View Article and Find Full Text PDFRadiat Environ Biophys
November 2019
The main goal of this study was to determine radiation interaction parameters such as mass attenuation coefficients, effective atomic numbers, and effective electron densities depending on element concentrations (Na, K, Cu, Zn, Al, Ca, Mg Cr, Fe, Se) in blood samples of patients with breast cancer. Eighty blood samples were collected and analyzed in this study (40 from breast cancer patients and 40 from healthy patients). The determination of element concentrations of the samples was performed with inductively coupled plasma-mass spectrometry (ICP-MS) and inductively coupled plasma-optical emission spectrometry (ICP-OES) after which the element concentrations were normalized to percentage.
View Article and Find Full Text PDFThe main purpose of this study was to investigate the relationship between the electron densities and Na/K ratio which has important role in breast cancer disease. Determinations of sodium and potassium concentrations in blood samples performed with inductive coupled plasma-atomic emission spectrometry. Electron density values of blood samples were determined via ZXCOM.
View Article and Find Full Text PDFObjective: The objective of this study was to establish which factor leads to a higher vestibulo-ocular reflex (VOR) gain: the timing of the movement or the direction of the movement. For this purpose, healthy volunteers were examined under three conditions: (1) when they were informed about the timing of the head movement; (2) when they were informed about the direction of the head movement; and (3) when they knew both the timing and the direction of the head movement.
Materials And Methods: This study included data from 19 participants between the ages of 20 and 23 years with no neurological or vestibular ailments.
The human cytomegalovirus (HCMV) is an important human pathogen primarily affecting immunocompromised patients, like transplant recipients or HIV- infected individuals. Early diagnosis of cytomegalovirus (CMV) infection in high-risk patients is essential in order to start preemptive treatments. pol (UL54) gene encoding for HCMV viral DNA polymerase is a well-defined target for HCMV detection in clinical samples and identifying most highly conserved regions for primer design remains crucial.
View Article and Find Full Text PDF