Evaluating the simultaneous electrochemical determination of antineoplastic drugs using LaNiO/g-CN@RGH nanocomposite material.

A novel electrochemical sensor based on LaNiO/g-CN@RGH nanocomposite material was developed to simultaneously determine Ribociclib (RIBO) and Alpelisib (ALPE). Ribociclib and Alpelisib are vital anticancer medications used in the treatment of advanced breast cancer. The sensor exhibited excellent electrocatalytic activity towards the oxidation of RIBO and ALPE, enabling their simultaneous detection.

Molecular mechanism of direct electron transfer in the robust cytochrome-functionalised graphene nanosystem.

Construction of green nanodevices characterised by excellent long-term performance remains high priority in biotechnology and medicine. Tight electronic coupling of proteins to electrodes is essential for efficient direct electron transfer (DET) across the bio-organic interface. Rational modulation of this coupling depends on in-depth understanding of the intricate properties of interfacial DET.

Imidazole substituted Zinc(II) phthalocyanines for co-catalyst-free photoelectrochemical and photocatalytic hydrogen evolution: influence of the anchoring group.

Novel zinc phthalocyanine derivatives, ZnPc-1 and ZnPc-2, consisting of one and four imidazole units, respectively, have been synthesized and utilized as panchromatic photosensitizers for photocatalytic and photoelectrochemical H evolution. The effect of the imidazole-anchoring group on the photocatalytic H production has been compared with ZnPc-3, which possesses a carboxylic acid unit as the anchoring group. ZnPc-1/TiO shows the best photoactivity with the highest H evolution rate of 0.

Development of a Novel Nanoarchitecture of the Robust Photosystem I from a Volcanic Microalga on Single Layer Graphene for Improved Photocurrent Generation.

Here, we report the development of a novel photoactive biomolecular nanoarchitecture based on the genetically engineered extremophilic photosystem I (PSI) biophotocatalyst interfaced with a single layer graphene via pyrene-nitrilotriacetic acid self-assembled monolayer (SAM). For the oriented and stable immobilization of the PSI biophotocatalyst, an His-tag was genetically engineered at the -terminus of the stromal PsaD subunit of PSI, allowing for the preferential binding of this photoactive complex with its reducing side towards the graphene monolayer. This approach yielded a novel robust and ordered nanoarchitecture designed to generate an efficient direct electron transfer pathway between graphene, the metal redox center in the organic SAM and the photo-oxidized PSI biocatalyst.

Investigation of the antifouling properties of polyethersulfone ultrafiltration membranes by blending of boron nitride quantum dots.

This study aims to investigate the modification of polyethersulfone (PES) membrane with boron nitride quantum dots (BNQD) for improving the antifouling performance. The composite membranes were synthesized by blending different amounts of BNQD (0.50, 1.

Enhancement of direct electron transfer in graphene bioelectrodes containing novel cytochrome c variants with optimized heme orientation.

The highly efficient bioelectrodes based on single layer graphene (SLG) functionalized with pyrene self-assembled monolayer and novel cytochromec(cytc)peptide linker variants were rationally designed to optimize the direct electron transfer (DET) between SLG and the heme group of cyt. Through a combination of photoelectrochemical and quantum mechanical (QM/MM) approaches we show that the specific amino acid sequence of a short peptide genetically inserted between the cytcholoprotein and thesurface anchoring C-terminal His-tag plays a crucial role in ensuring the optimal orientation and distance of the heme group with respect to the SLG surface. Consequently, efficient DET occurring between graphene and cyt c leads to a 20-fold enhancement of the cathodic photocurrent output compared to the previously reported devices of a similar type.

Subphthalocyanine-sensitized TiO photocatalyst for photoelectrochemical and photocatalytic hydrogen evolution.

A series of SubPcs comprising a carboxylic acid anchoring group at the peripheral (SubPcs 1, 2) or axial position (SubPc 3) were synthesized and used as sensitizers for photocatalytic H2 production, for the first time. SubPc 3/TiO2 shows the best photocatalytic activity with a hydrogen evolution rate of 1396 μmol h-1, which is much higher than that of SubPcs 1 and 2 (771 and 658 μmol g-1, respectively). This work clearly shows that considering their optical and redox properties, SubPcs are promising candidates for light-driven water splitting systems.

Preparation and evaluation of effect on Escherichia coli and Staphylococcus aureus of radiolabeled ampicillin-loaded graphene oxide nanoflakes.

Ampicillin is a one of effective antibiotics against Gram-positive and Gram-negative bacteria. This study aimed to label ampicillin-loaded graphene oxide nanoflake (AMP-GO) with Tc and evaluate of its in vitro binding to Staphylococcus aureus and Escherichia coli. Firstly, ampicillin was loaded into graphene oxide nanoflake prepared.

Synergetic effects of Fe doped spinel LiTiO nanoparticles on reduced graphene oxide for high surface electrode hybrid supercapacitors.

In this work, reduced graphene oxide (rGO) based electrode materials were developed to achieve a hybrid supercapacitor (SC) function. Therefore, several synthesis methods were developed to prepare a cost effective and environmentally friendly rGO. Additionally, to maintain the high surface area, spinel lithium titanate (sLTO) nanoparticles (NPs) were synthesized and deposited on the rGO surface to inhibit the restacking of the rGO layers on graphite.

High-Capacitance Hybrid Supercapacitor Based on Multi-Colored Fluorescent Carbon-Dots.

Multi-colored, water soluble fluorescent carbon nanodots (C-Dots) with quantum yield changing from 4.6 to 18.3% were synthesized in multi-gram using dated cola beverage through a simple thermal synthesis method and implemented as conductive and ion donating supercapacitor component.

Synthesis and performance of antifouling and self-cleaning polyethersulfone/graphene oxide composite membrane functionalized with photoactive semiconductor catalyst.

This study was performed to synthesize membranes of polyethersulfone (PES) blended with graphene oxide (GO) and PES blended with GO functionalized with photoactive semiconductor catalyst (TiO and ZnO). The antifouling and self-cleaning properties of composite membranes were also investigated. The GO was prepared from natural graphite powder by oxidation method at low temperature.

A nanoscale bio-inspired light-harvesting system developed from self-assembled alkyl-functionalized metallochlorin nano-aggregates.

Self-assembled supramolecular organization of nano-structured biomimetic light-harvesting modules inside solid-state nano-templates can be exploited to develop excellent light-harvesting materials for artificial photosynthetic devices. We present here a hybrid light-harvesting system mimicking the chlorosomal structures of the natural photosynthetic system using synthetic zinc chlorin units (ZnChl-C6, ZnChl-C12 and ZnChl-C18) that are self-aggregated inside the anodic aluminum oxide (AAO) nano-channel membranes. AAO nano-templates were modified with a TiO2 matrix and functionalized with long hydrophobic chains to facilitate the formation of supramolecular Zn-chlorin aggregates.