Melatonin protects kidney against apoptosis induced by acute unilateral ureteral obstruction in rats.

Introduction: To investigate whether there was a protective effect of melatonin on apoptotic mechanisms after an acute unilateral obstruction of the kidney.

Material And Methods: A total of 25 rats consisting of five groups were used in the study, designated as follows: Group 1: control, Group 2: sham, Group 3: unilateral ureteral obstruction treated with only saline, Group 4: unilateral ureteral obstruction treated with melatonin immediately, and Group 5: unilateral obstruction treated with melatonin one day after obstruction. Melatonin was administered as a 10 mg/kg dose intraperitoneally.

The effectiveness of local steroid injection after internal urethrotomy to avoid recurrence.

Objective: Local steroid injection to the stricture region after internal urethrotomy (IU) is a promising technique to avoid the recurrence, although the effectiveness and safety of this technique is still controversial. We aimed to determine the efficacy and safety of local steroids as applied with the IU procedure.

Material-method: A total of 83 patients data with urethral stricture in men were examined retrospectively.

What is harmful for male fertility: cell phone or the wireless Internet?

In this study, we aimed to assess the potential harmful effects of radiofrequency-electromagnetic radiation on sperm parameters. We requested semen for analyses from the male patients coming to our infertility division and also asked them to fill out an anonymous questionnaire. We queried their mobile phone and wireless Internet usage frequencies in order to determine their radiofrequency-electromagnetic radiation exposure.

The comparison of the influence between two different bowel preparation methods on sepsis after prostate biopsies.

Introduction: Transrectal ultrasonography (TRUS) guided prostate needle biopsy has been performed to diagnose and stage prostate cancer for many years. There are many different bowel preparation protocols to diminish the infectious complications, but there is no standardized consensus among urologists. Therefore, we aimed to assess two different bowel preparation methods on the rate of infectious complications in patients who underwent TRUS-guided prostate biopsy.

The association between serum follicle-stimulating hormone levels and the success of microdissection testicular sperm extraction in patients with azoospermia.

Purpose: To evaluate the predictive power of luteinizing hormone (LH), follicle-stimulating hormone (FSH), testosterone, testicular biopsy histology and male age were evaluated with respect to the success of sperm retrieval in a microdissection testicular sperm extraction (microTESE) procedure, pregnancy and live birth rates.

Materials And Methods: We examined the data of 131 infertile men with non-obstructive azoospermia, who have undergone microTESE operation. The men were classified into two groups based on serum follicle-stimulating hormone (FSH) levels ≤ 15 mIU/mL (group 1) and > 15 mIU/mL (group 2).

Bladder cancer invasion predictability based on preoperative neutrophil-lymphocyte ratio.

An increased pretreatment neutrophil-lymphocyte ratio (NLR) is associated with poor prognosis in colorectal, gastric, and ovarian cancer; malignant mesothelioma; and renal cell carcinoma. The present study aims to define the predictive value of preoperative peripheral blood count NLR in non-muscle-invasive bladder cancer (NMIBC) and muscle-invasive disease (MIBC) patients. There were in total 291 patients, 241 males and 50 females.

Is polycystic ovarian syndrome a risk factor for urolithiasis?

Urinary stone disease is a complex multifactorial disorder influenced by both intrinsic and environmental factors. It is generally known that age and sex are risk factors for urinary stone disease. Also men have higher mean urinary oxalate concentrations than women.

Helicobacter pylori seroprevalence in patients with chronic prostatitis: a pilot study.

Objective: This study investigated the possible relationship between Helicobacter pylori infection and chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS). The rate of seropositivity for antibodies against H. pylori was determined in a cohort of subjects with CP/CPPS and prostatitis-free control subjects.

The evaluation of clitoral blood flow and sexual function in elite female athletes.

Introduction: Clitoral blood flow measurements using clitoral color Doppler ultrasound have been performed with increasing frequency either in order to assessment of female sexual function/dysfunction. The trials to evaluate the sexual function in healthy subjects, especially in the subgroup of female elite athletes, are limited.

Aim: The aim of the study was to evaluate whether elite female athletes and sedentary healthy females differ in their clitoral blood flow and sexual function as an expression of their physical fitness status.

An insidious risk factor for cardiovascular disease: benign prostatic hyperplasia.

Patients with benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTSs) have a considerably higher prevalence of cardiovascular disease (CVD) than the general population in old age. Many hypotheses have been created to explain traditional clinical risk factors of CVD, including age, male gender, cigarette smoking, inheritance, high blood pressure (BP), obesity, elevated fasting plasma glucose, diabetes mellitus, dyslipidemia, decreased physical activity and metabolic syndrome; or nontraditional risk factors such as oxidative stress, inflammation, vascular calcification, malnutrition, homocysteine and genetic variation. Although these risk factors are important in CVD pathophysiology and clinical presentation, there is still no single theory sufficient to provide an adequate explanation for all the properties of CVD.

Ovarian apoptosis after shock wave lithotripsy for distal ureteral stones.

The objective of this study is to identify any apoptotic effect of shock wave lithotripsy (SWL) for distal ureteral stones on ovarian tissue. Twenty-one female New Zealand White rabbits were divided into three groups of seven rabbits each: I (control), and II, III (treated and killed 14 and 28 days after SWL, respectively). The left distal ureteral segment of the anesthetized (ketamine HCl, 20 mg/kg) animals in groups II and III was exposed to 1,500 shock waves at 17 kV.

Curcumin protects against ischemia/reperfusion injury in rat kidneys.

Objectives: Renal ischemia followed by reperfusion leads to acute renal failure in both native kidneys and renal allograft. We investigated the effect of curcumin on ischemia-reperfusion (I/R) injury and the antioxidant effects of curcumin in rats.

Methods: Thirty rats were randomly divided into five experimental groups (control, sham, curcumin, I/R and I/R+curcumin, n=6 each).

Nigella sativa protects against ischaemia/reperfusion injury in rat kidneys.

Background: Renal ischaemia followed by reperfusion leads to acute renal failure in both native kidneys and renal allografts, which is a complex pathophysiologic process involving hypoxia and free radical (FR) damage. The oil of Nigella sativa (NSO) has been subjected to considerable pharmacological investigations that have revealed its antioxidant activity in different conditions. But there is no previously reported study about its effect on ischaemia/reperfusion (I/R) injury of kidneys.

Oral beta-glucan protects kidney against ischemia/reperfusion injury in rats.

Background: Ischemia-reperfusion (I/R) injury is one of the leading causes of acute renal failure. Beta-(1-->3)-glucans are glucose polymers with a variety of stimulatory effects on the immune system. We designed this study to determine the possible protective effect of the orally administered soluble beta-glucan against I/R injury.

The effects of shock waves on lung tissue in acute period: an in vivo study.

The acute effects of extracorporeal shock waves on lung morphology were studied by light microscopy in 30 New Zealand rabbits. The left kidneys of the ten animals were exposed to 2,000 shockwaves at 18 kV under anesthesia (ESWL group). Ten rabbits were in the control group; an intramuscular anesthetic agent (ketamine) and intravenous contrast media were administered to ten animals in the sham group.

Rapid communication: renal apoptosis after shockwave application in rabbit model.

Purpose: To identify any apoptotic effect of shockwave lithotripsy (SWL) on renal tubular and glomerular cells.

Materials And Methods: Thirty-five male New Zealand White rabbits were divided into five groups of seven rabbits each: I (control), II (sham), and III, IV, and GV (treated and sacrificed 1, 7, and 28 days after SWL, respectively). Intramuscular anesthetic agent (ketamine HCl; 20 mg/kg) and intravenous contrast medium (iohexol 300 mg of I/mL) were administered to animals in group II.

Is single-dose fosfomycin trometamol a good alternative for asymptomatic bacteriuria in the second trimesterof pregnancy?

Untreated asymptomatic bacteriuria has been associated with acute pyelonephritis, which may have a role in many maternal and fetal complications. Acute pyelonephritis in pregnancy is related to anemia, septicemia, transient renal dysfunction, and pulmonary insufficiency. A randomized study was conducted to assess the clinical and microbiological efficacy of a single dose of fosfomycin trometamol for the treatment of asymptomatic bacteriuria in the second trimester of pregnancy compared with a 5-day regimen of cefuroxime axetyl.

Protective role of natural antioxidant supplementation on testicular tissue after testicular torsion and detorsion.

Objectives: To investigate the impact of garlic extract (GE), which is known for its antioxidant activity, on a testicular torsion/detorsion model in animals and to help understand how to prevent both ischemic and reperfusion injuries after testicular torsion and detorsion.

Material And Methods: Six groups of rats (n=7 in each group) were used. The animals in the control group (Group I) did not receive any treatment.

Malignant fibrous histiocytoma arising from the renal capsule.

We report a case of malignant fibrous histiocytoma arising from the renal capsule which is a rare condition. The patient was treated with surgical excision of the tumor including the renal capsule and subsequent radiotherapy of 6,600 rad. No recurrence was detected 15 months after surgery.

The actual incidence of bladder perforation following transurethral bladder surgery.

Purpose: In this prospective study we evaluated the incidence of bladder perforation after transurethral bladder tumor resection.

Materials And Methods: A total of 36 patients (33 male, 3 female, mean age +/- SD 65.6 +/- 11.

Temporary urethral stenting for membranous urethral stricture helps complete healing without compromising continence.

We report the case of a patient with a recurrent membranous urethral stricture who was treated with temporary implantation of a UroLume endoprosthesis and recovered completely, without any sphincteric insufficiency or stricture recurrence, during a 1-year follow-up period.

Voiding position does not affect uroflowmetric parameters and post-void residual urine volume in healthy volunteers.

Objective: To investigate the effect of voiding position using uroflowmetry and post-void residual (PVR) urine volume assessment in healthy men and women.

Material And Methods: The study population comprised 72 healthy volunteers. The mean (range) ages of the male (n = 36) and female (n = 36) subjects were 30 (18-40) years and 32 (21-44) years, respectively.

Urethral adenocarcinoma mimicking urethral caruncle.

Urethral caruncles are considered as benign tumors. They need to be treated surgically; specimens should carefully be evaluated for the presence of any malignancy. We are presenting a 57-year-old female patient with a urethral lesion that looks like caruncle, but histopathologic examination of the excised lesion was reported as urethral adenocarcinoma.