Objective: The aim of this study was to assess the effects of tranexamic acid on fracture healing in the rat tibia closed fracture model.
Methods: Sixty-four male Sprague-Dawley rats were included in this study, where closed fracture and intramedullary nailing were performed on their right tibial diaphyses. They were divided into 2 main groups, the experimental group, which was given weekly tranexamic acid injections, and the control group, which received no additional treatment.
Objectives: To develop a reproducible experimental animal model for sulcus vergeture in rabbits.
Study Design: Experimental animal study.
Material Method: We evaluated three methods of inducing sulcus in twelve New Zealand white rabbits to produce a sulcus model.
Objectives: The purpose of this study is to shorten the decellularization time of trachea by using combination of physical, chemical, and enzymatic techniques.
Methods: Approximately 3.5-cm-long tracheal segments from 42 New Zealand rabbits (3.
Background: Pseudoangiomatous stromal hyperplasia (PASH) is a benign lesion of myofibroblasts that is composed of a network of slit-like channels that resemble vascular spaces. The aims of this study were to document the frequency of PASH in core needle biopsy specimens (CNBS) of the breast, to describe which histopathologic findings coexist with PASH and to examine any endothelial cell differentiation.
Materials And Methods: We reevaluated hematoxylin and eosin-stained sections of all CNBS that were obtained during a 1-year period.
Acta Orthop Traumatol Turc
February 2017
Objective: The aim of this study was to evaluate the impact of the timing of platelet-rich plasma (PRP) application on the healing of Achilles tendon injury in a rat model.
Methods: Fifty-four female Sprague-Dawley rats were divided into 4 groups: PRP preparation group (n=6); Achilles tendon tear and 150 µL of PRP received on the day following the injury (PRP day 0, group 1, n=16); Achilles tendon tear and 150 µL of PRP received on the third day following injury (day 3 , group 2, n=16); Achilles tendon tear and 150 µL of saline received on the day following injury (PRP day 0, group 3, n=16). Rats were sacrificed at 3 weeks.
Chondroblastoma is a highly destructive tumor originating from immature cartilage cells. Although chondroblastoma is defined as a benign tumor, it may exhibit malign tumor behaviors such as invasion or metastasis on neighboring structures. Magnetic resonance (MR) image is a solid mass lesion, which included heterogeneous hypointense in T2A and heterogeneous minimal hyperintense in T1A with destructive expansile characteristics and millimetric calcifications.
View Article and Find Full Text PDFPseudoangiomatous stromal hyperplasia (PASH) is a benign proliferative entity of mammary stroma. It is generally found as an incidental finding. It may rarely present as a palpable nodule.
View Article and Find Full Text PDFPrimary tumors of the paratesticular region are rare, with paratesticular sarcomas constituting a major proportion of these tumors, particularly in the elderly. The paratesticular region consists of mesothelial, various epithelial and mesenchymal cells and may therefore give rise to a number of tumors with various behaviors. Defining the association between the paratesticular mass and the testicle, and differentiation between benign and malignant masses using radiology is challenging, therefore the mass is usually considered to be malignant and radical orchiectomy with high ligation is performed.
View Article and Find Full Text PDFSplenic epidermoid cyst is a rare cystic disease of spleen. Primary cysts of the spleen lined by epithelium or endothelium are usually seen in young adults. A 23-year-old woman with abdominal distension presented at the surgery outpatients of our hospital.
View Article and Find Full Text PDFObjective: To determine the effects of ibuprofen (Ibp) on the vessel proliferation and necrosis in a rat glioma model.
Study Design: Experimental, randomized interventional trial.
Place And Duration Of Study: 1st Neurosurgery Clinic in Bakirkoy Mental Diseases Hospital, Bakirkoy, Istanbul, Turkey, in the year 2010.
Purpose: Temozolomide (TMZ) has anti-tumor activity in patients with malignant glioma. Hyperbaric oxygen (HBO) may enhance the efficacy of certain therapies that are limited because of the hypoxic tumor microenvironment. We examined the combined effects of TMZ-HBO in a rat glioma model.
View Article and Find Full Text PDFBackground/aims: Sclerosing cholangitis is a rare complication of Langerhans cell histiocytosis in children which can result in liver failure. This combination is even rarer in adults.
Case Report: We report a 65-year-old female who developed sclerosing cholangitis 4 years after the diagnosis of Langerhans cell histiocytosis.