Publications by authors named "Erol Coskun"
Aims: To investigate whether ondansetron use during pregnancy is associated with increased rates of major or subgroups of malformations.
Methods: PubMed/MEDLINE, Cochrane and Reprotox databases were searched. Observational studies comprising an exposed and control group (healthy and/or disease-matched) were included.
Objective: To investigate whether maternal exposure to quinolones, fluoroquinolones and specifically ciprofloxacin is associated with major malformations and other adverse pregnancy outcomes.
Methods: MEDLINE/PubMed, Embase and Reprotox® databases were searched. Observational studies with an exposed and control group were included.
Objective: To investigate the pregnancy outcomes of women who were exposed to betahistine during their pregnancies.
Methods: We identified and evaluated the outcomes of 27 pregnant women who were referred to Terafar (Teratology Information Service, Izmir, Turkey) for a teratological risk assessment.
Results: Of 24 pregnancies with known outcomes, 21 resulted in live births (including two pairs of twins) whereas two ended with miscarriage and three with elective terminations.
Purpose: To analyze the data of patients who underwent vitreoretinal surgery due to intraocular foreign body (IOFB) injuries that occurred in the Syrian civil war.
Methods: Seventy-eight eyes of 78 patients who underwent vitreoretinal surgery due to IOFB injuries that occurred during the Syrian civil war were analyzed.
Results: Forty-four eyes (56.
Purpose: To describe a new surgical modified procedure in patients with chronic total oculomotor nerve palsy and to evaluate the results of this procedure.
Methods: Eight eyes of 6 consecutive patients who underwent strabismus surgery due to chronic total oculomotor nerve palsy were enrolled in the study. The lateral rectus muscle was split into two halves and disinserted from the sclera.
The annual economic burden of visual disorders in the United States was estimated as $139 billion. The World Health Organization has listed glaucoma in the top 10 priority eye diseases. Primary open-angle glaucoma (POAG) is a common subtype, with a lack of clinical tools for early diagnosis.
View Article and Find Full Text PDFThe objective of this study was to analyze the characteristics and surgical results of pediatric rhegmatogenous retinal detachment (RRD). The medical records of 30 eyes of 29 patients younger than 18 years of age who underwent vitreoretinal surgery due to RRD were analyzed. The gender, age, laterality, duration of presenting symptom, etiology, ocular and systemic co-morbidities, type of breaks, lens status, presence of proliferative vitreoretinopathy (PVR) and its grade, initial and final best-corrected visual acuities (BCVAs), surgical management, number of operations, duration of follow-up, functional and anatomical success, and complications were noted.
View Article and Find Full Text PDFArticle Synopsis
- The study explored the effectiveness of a dexamethasone (DEX) implant for treating stubborn cases of Behçet posterior uveitis in patients.
- A group of 12 patients received a single DEX implant injection, with their vision and eye conditions monitored over a year.
- Results showed significant improvements in visual acuity, reduction in central macular thickness, and decreased vitreous haze, indicating the treatment's safety and efficacy.
Purpose: To evaluate the effectiveness of liquid crystal glasses (LCG) in the treatment of children with monocular amblyopia.
Methods: A total of 14 amblyopic eyes of 14 children with monocular amblyopia were enrolled in the study. LCG with appropriate refractive correction were ordered for each patient.
Purpose: To investigate whether there is an association between penetrating eye injuries and attention deficit hyperactivity disorder (ADHD) symptoms in children.
Methods: 45 children aged 3-18 years who were treated due to penetrating ocular injuries (patient group) and 75 control subjects (control group) were enrolled in the study. The symptoms of ADHD were evaluated by the Turkish adapted and validated form of the Conner Parent Rating Scale (CPRS).
Aim: To investigate choroidal thickness in healthy Turkish subjects.
Materials And Methods: Refraction, axial length (AXL) measurement, anterior chamber, and fundus examinations were performed. Eyes that had any retinal or choroidal pathology were excluded from the study.
Objective: To evaluate the visual and refractive outcomes after phacoemulsification surgery in eyes with isolated lens coloboma.
Design: Prospective, consecutive case series.
Participants: Eighteen eyes with isolated lens coloboma of 13 patients were included in the study.
Background: Corrective surgery is done for ocular alignment and disrupted facial expression in some cases of adult strabismus patients. The effects of corrective surgery on the presence of social phobia (SP) diagnosis, the severity of social anxiety symptoms, the disease-related disability and the quality of life (QoL) among strabismus patients have not been thoroughly studied yet.
Methods: The study sample was composed of patients who had undergone corrective surgery for strabismus.
Purpose: Genetic factors are shown to have a role in the development of primary open-angle glaucoma (POAG). The aim of this study was to determine the effects of genetic polymorphisms of Rho-kinase (ROCK) genes on the risk of POAG in a Turkish population.
Methods: Genomic DNA was extracted from leukocytes of the peripheral blood, and 8 single nucleotide polymorphisms in the ROCK1 and ROCK2 genes were analysed in 179 patients with POAG and in 182 healthy controls of similar age by using BioMark HD dynamic array system.
Purpose: Genetic factors are shown to have a role in the development of primary open angle glaucoma (POAG). The aim of this study was to determine the effects of genetic polymorphisms of transient receptor potential melastatin (TRPM) channel genes on the risk of POAG in a Turkish population.
Methods: Genomic DNA was extracted from the leukocytes of the peripheral blood, and 26 single nucleotide polymorphisms in the TRPM channel genes were analyzed in 179 patients with POAG and in 182 healthy controls of similar age by using the BioMark HD dynamic array system.
Enhanced depth imaging optical coherence tomography findings in Behçet disease.
Ocul Immunol Inflamm
December 2013
Purpose: Investigation of subfoveal choroidal thickness in Behçet disease (BD) with enhanced depth imaging optical coherence tomography (EDI-OCT).
Methods: The study included 35 patients with posterior uveitis (PU) associated with BD, 35 patients with BD without ocular involvement, and 30 healthy controls.
Results: There were no significant differences between the groups in terms of age, gender, axial length, or spherical equivalent refractive error.
Purpose: To compare bactericidal activities of daptomycin and vancomycin in an experimental rabbit model of methicillin-resistant Staphylococcus aureus (MRSA) endophthalmitis.
Methods: The right eyes of 19 New Zealand rabbits weighing 2 to 2.5 kg were used.
Background: To evaluate the treatment with topical 0.05% cyclosporine A (CsA) in patients with subepithelial corneal infiltrates (SEI).
Methods: We reviewed 16 patients (22 eyes) before and after the treatment with 0.
Hydroa vacciniforme (HV) is a sporadic, rare and idiopathic chronic photodermatosis characterized by recurrent vesicles and crust formation on a sun-exposed skin, typically resulting in vacciniform or varioliform scarring. Herein, we report on a 18-year-old boy who presented with rare ocular involvement in HV.
View Article and Find Full Text PDFPurpose: The aim of this study was to show the efficiency of preoperative botulinum toxin A (Botox A) in patients with benign essential blepharospasm who were to undergo ocular surgery with local anesthesia.
Materials And Methods: Twenty-eight benign essential blepharospasm patients who were administered unilateral Botox A prior to ocular surgery between January 2004 and May 2011 were included in this study. Eleven cases had pterygiums, ten had cataracts, and four had glaucomas, while the remaining three had aphakia.
Purpose: To evaluate possible role of the UTS2 gene polymorphisms (Thr21Met and Ser89Asn) in the genetic susceptibility to diabetic retinopathy (DR) in a Turkish population.
Methods: Total number of 280 patients with DR (nonproliferative DR 170 and proliferative DR 110), 291 nondiabetic healthy controls, and 113 diabetic controls (without DR) were included to this study. The detection of UTS2 gene polymorphisms was achieved with PCR-RFLP technique.
Purpose: To show the efficiency of repetitive probing performed with intranasal endoscopic imaging in cases who underwent unsuccessful probing and the accompanying nasal pathologies.
Methods: Eighty-four eyes of the 64 patients in whom primary probing was found to be unsuccessful were included in the study. Cases were divided into 3 groups, depending on the number of unsuccessful attempts (1 [group 1], 2 [group 2], and 3 [group 3] unsuccessful probings).
Purpose: To compare the results of penetrating keratoplasty (PK) in a series of congenital hereditary endothelial dystrophy (CHED) patients operated at amblyogenic years and at later ages.
Methods: Records of 65 eyes of 35 CHED patients who underwent PK were reviewed retrospectively. Visual results and graft clarity rates were compared between patients operated after (group 1) and before (group 2) 12 years of age.