Biomimetic in vitro test system for evaluation of dental implant materials.

Objectives: Before application in dental practice, novel dental materials are tested in vitro and in vivo to ensure safety and functionality. However, transferability between preclinical and clinical results is often limited. To increase the predictive power of preclinical testing, a biomimetic in vitro test system that mimics the wound niche after implantation was developed.

Evaluation of model materials for CAD/CAM in vitro studies.

Aim: Evaluation of appropriate models for computer-aided design/computer-aided manufacturing (CAD/CAM) in vitro studies by investigation of different model materials regarding suitability for intraoral scanners and dimensional stability.

Materials And Methods: A typodont model was prepared to accommodate a 10-unit prosthesis. The model was duplicated using six different materials: class IV die stone (DS), cobalt-chrome molybdenum (CoCrMo), epoxy resin (EPOX), polyurethane (PU), titanium (TI), and zirconia (ZI).