Publications by authors named "Ernst Wisse"

Background: People who inject drugs (PWID) in Kachin, Myanmar, have a high HIV prevalence (>40%), but there is no data on incidence. We used HIV testing data from three harm reduction drop-in centres (DIC) in Kachin (2008-2020) to determine HIV incidence trends among PWID and associations with intervention uptake.

Methods: Individuals were HIV-tested at first DIC visit and periodically thereafter, during which demographic and risk behaviour data were collected.

View Article and Find Full Text PDF
Article Synopsis
  • PWID in Kenya face high rates of HIV (14-26%) and hepatitis C (11-36%), prompting an evaluation of the effectiveness of current and enhanced treatment strategies.
  • A model was used to analyze the potential benefits of existing therapies like antiretroviral therapy (ART), opioid agonist therapy (OAT), and needle syringe programs (NSP) as well as proposed strategies for harm reduction and increased treatment over the next decade.
  • Results showed that while existing interventions significantly reduced HIV and HCV infections, achieving substantial reductions by 2030 will require scaling up these interventions along with measures to decrease sexual risk and an increased focus on HCV treatment.
View Article and Find Full Text PDF

Introduction: People who inject drugs (PWID) in Dar es Salaam, Tanzania, have a high prevalence of HIV and hepatitis C virus (HCV). While needle and syringe programmes (NSP), opioid agonist therapy (OAT) and anti-retroviral therapy (ART) are available in Tanzania, their coverage is sub-optimal. We assess the impact of existing and scaled up harm reduction (HR) interventions on HIV and HCV transmission among PWID in Dar es Salaam.

View Article and Find Full Text PDF

Background: Kabul has over 12,000 people who inject drugs (PWID), most of them heroin users, and opioid substitution therapy has recently been introduced as an effective method to reduce opioid use. We aimed to evaluate a pilot Opioid Substitution Therapy Pilot Program (OSTPP) in Kabul, Afghanistan, particularly to (1) describe characteristics of the participants enrolled in the program and (2) identify factors associated with client retention in the OSTPP.

Findings: Two cross-sectional surveys evaluated participants attending the OSTPP at baseline (n = 83) and 18 months after (n = 57).

View Article and Find Full Text PDF