Publications by authors named "Ernesto Romero-Lopez"
Int J Mol Sci
October 2024
Article Synopsis
- Hereditary mutations, like those in the tumor protein 53 gene, can lead to Li-Fraumeni syndrome (LFS), increasing the risk of multiple cancers due to a precancerous environment, with limited treatment options currently available.
- Recently, metformin has been explored as a possible preventative medication targeting precancerous niches, but is still in clinical trials and lacks established treatments.
- A case study on a patient with LFS who took H387 07 extract for 11 years showed no new malignancies, suggesting polyphenol-rich extracts might be effective for cancer prevention and treatment in LFS patients.
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