Publications by authors named "Ernest U Durugbo"
Bioaerosols, a significant yet underexplored component of atmospheric particulate matter, pose substantial public health risks, particularly in regions with poor air quality. This study investigates the composition of bioaerosols in public spaces, specifically two interstate motor parks and two marketplaces in Osun State, Nigeria, over six months. Air samples were collected, and bacterial and fungal species were identified, focusing on pathogenic organisms.
View Article and Find Full Text PDFCharacterization, Anti-glycation, Anti-inflammation, and Lipase Inhibitory Properties of Rauvolfia vomitoria Leaf Extract: In Vitro and In Silico Evaluations for Obesity Treatment.
Appl Biochem Biotechnol
October 2024
Article Synopsis
- Pancreatic lipase (PLP) is an enzyme that breaks down fats, and inhibiting it could help manage obesity, leading to research on safer natural inhibitors due to side effects from traditional ones.
- The study tested the effects of extracts from Rauvolfia vomitoria leaves (aqueous, ethanolic, and methanolic) on anti-glycation, anti-inflammatory, and lipase inhibition using lab techniques to analyze the compounds' properties.
- Among the extracts, the methanolic one (MRV) showed the strongest PLP inhibition and interacted effectively with the enzyme, suggesting potential for a natural obesity treatment and insights into drug design.
Introduction: Non-albicans species (NACS) have emerged as a major public health burden, although they are still underappreciated. Some NACS have intrinsic antifungal resistance, requiring constant surveillance to improve patient care and thwart outbreaks of recalcitrant candida infections. However, effective species surveillance has relied on PCR-based or other high-end techniques that are largely unaffordable in under-resourced countries.
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