Chronobiological variations of acute aortic dissection in a Northwest Chinese population.

Background: The prevalence of acute aortic dissection (AAD) has been gradually increasing in recent years. This study aimed to investigate the circadian variations of AAD onset in a northwest Chinese population and provide scientific insights for AAD prevention.

Methods: The clinical data of 1,145 AAD patients admitted to our hospital between January 2010 and December 2020 were retrospectively collected, and the periodic features of AAD were analyzed.

One-stop hybrid surgery for treatment of complex Stanford type B aortic dissection.

Objectives: To compare the efficacy and prognosis of one-stop hybrid surgery using the elephant trunk procedure for treatment of complex Stanford type B aortic dissection.

Methods: We retrospectively analyzed patients who underwent surgical treatment from January 2014 to July 2019. The patients were divided into those who underwent the elephant trunk procedure (n = 10) and those who underwent one-stop hybrid surgery (n = 10).

Fistula between the right pulmonary artery and the left atrium coexisting with a secundum-type atrial septal defect: An unusual case of cyanosis in a girl.

A fistula between the pulmonary artery (PA) and the left atrium (LA) is a rare congenital heart disease that usually presents with cyanosis, clubbing, and dyspnea, as well as the signs and symptoms of a right-to-left shunt. Herein, we report a 16-year-old girl with a fistula between the right PA and the LA. This type of fistula could lead to systemic desaturation.

Double-chambered left ventricle: A rare case in a child.

Double-chambered left ventricle (DCLV) is an extremely rare congenital heart disease. In this condition, the left ventricle is divided into two chambers by a septum or muscle fiber with abnormal proliferation. A symptomatic boy was diagnosed with DCLV at our hospital.

A rare case of biventricular myxoma.

Background: Cardiac myxoma is the most common primary cardiac tumor. Approximately 75-80% of myxomas are located in the left atrium. Occurrence of multiple myxomas is extremely rare.

Mechanisms of Apoptin-induced cell death.

Apoptin, a 13.6-kD protein encoded by chicken anemia virus, is paid more and more attention, since it selectively induces apoptosis in tumor cells while abolishes cytotoxic effect in normal cells. In addition, Apoptin shows different localization in tumor cells and normal cells: it predominantly accumulates in nucleus of tumor cells, whereas in normal cells, it is detected mainly in cytoplasm.

[Expression and clinical significance of Nrf2 in esophageal squamous cell carcinoma].

Aim: To study the expression and clinical significance of Nrf2 (Nuclear factor E2 p45-related factor 2) in esophageal squamous cell carcinoma (ESCC).

Methods: The expression of Nrf2 in 32 cases of EC tissues, 30 cases of adjacent tissues, 21 positive Lymph node tissues and 24 negative Lymph node tissues was assessed by SP immunohistochemical method.

Results: The main location of Nrf2 was nuclear, and the positive rates of Nrf2 in the cancer tissues was 78.

[Effects of antidiabetic drug metformin on human breast carcinoma cells with different estrogen receptor expressing in vitro].

Aim: To research different effects of human breast carcinoma cells with different estrogen receptor expressing by antidiabetic drug metformin, and preliminary explore the possible underlying molecular mechanisms.

Methods: Cells were treated with metformin. Growth inhibition rates of the cells were measured by MTT assay.