Numerical simulation of stratospheric QBO impact on the planetary waves up to the thermosphere.

With the help of numerical simulation, a detailed analysis of the dynamical effect of the stratospheric quasi-biennial oscillation (QBO) of the equatorial zonal wind on the planetary waves (PWs) up to thermospheric heights is carried out for the first time. The 3-dimensional nonlinear mechanistic model of middle and upper atmosphere (MUAM) is used, which is capable of simulating the general atmospheric circulation from the surface up to 300-400 km altitude. The amplitudes of stationary and westward travelling PWs with periods from 4 to 10 days are calculated based on ensembles of model simulations for conditions corresponding to the easterly and westerly QBO phases.

Comorbidity profile of patients with concurrent diagnoses of asthma and COPD in Germany.

The aim of this study was to estimate the prevalence of concurrent diagnoses of asthma/COPD and examine its full spectrum of comorbid disorders in Germany. We used nationwide outpatient claims data comprising diagnoses of all statutory health insurees (40+ years) in 2017 (N = 40,477,745). The ICD-10 codes J44 (COPD) and J45 (asthma) were used to identify patients.

[Possible use of carbon nanotubes as taggants in gunpowder for small firearms cartridges].

The purpose of the work is to study the possibility of using carbon nanotubes (CNT) as taggants in gun powder to provide expert differentiation of used small firearms cartridges; and to identify the main characteristics of the changes to carbon nanotubes under firing conditions, i.e. short-term exposure to high temperatures and pressures.

Psychiatric and Nonpsychiatric Comorbidities Among Children With ADHD: An Exploratory Analysis of Nationwide Claims Data in Germany.

This study examined the full spectrum of comorbid disorders in all statutory-health-insured children aged 5 to 14 years with ADHD in 2017 by using nationwide claims data in Germany. Children with ADHD ( = 258,662) were compared for the presence of 864 comorbid diseases with a control group matched by gender, age, and region of residence ( = 2,327,958). Among others, metabolic disorders (odds ratio [OR] = 9.

Efficacy of microsurgery in Reinke's oedema evaluated by traditional voice assessment integrated with the Vocal Extent Measure (VEM).

There are few data analysing to what specific extent phonomicrosurgery improves vocal function in patients suffering from Reinke's oedema (RE). The recently introduced parameter vocal extent measure (VEM) seems to be suitable to objectively quantify vocal performance. The purpose of this clinical prospective study was to investigate the outcomes of phonomicrosurgery in 60 RE patients (6 male, 54 female; 56 ± 8 years ([mean ± SD]) by analysing its effect on subjective and objective vocal parameters with particular regard to VEM.

Efficacy of Phonosurgery, Logopedic Voice Treatment and Vocal Pedagogy in Common Voice Problems of Singers.

Introduction: Functional and organic impairments of the singing voice are common career-threatening problems of singers presenting in phoniatric and laryngological departments. The objective was to evaluate the efficacy of phonosurgery, logopedic voice treatment and vocal pedagogy in common organic and functional voice problems of singers, including investigation of the recently introduced parameter vocal extent measure (VEM).

Methods: In a prospective clinical study, the analysis of treatment outcome in 76 singers [57 female, 19 male; 38 ± 11 years (mean ± SD)] was based on pre- and post-therapeutic voice function diagnostics and videolaryngostroboscopy.

Phonomicrosurgery in Vocal Fold Nodules: Quantification of Outcomes in Professional and Non-Professional Voice Users.

Unlabelled: There are few data demonstrating the specific extent to which surgical intervention for vocal fold nodules (VFN) improves vocal function in professional (PVU) and non-professional voice users (NVU). The objective of this study was to compare and quantify results after phonomicrosurgery for VFN in these patient groups.

Methods: In a prospective clinical study, surgery was performed via microlaryngoscopy in 37 female patients with chronic VFN manifestations (38±12 yrs, mean±SD).

[Patient-sharing networks : New approaches in the analysis and transformation of geographic variation in healthcare].

The analysis of geographic variations has spurred arguments that area of residence determines access to and quality of healthcare. In this paper we argue that unwarranted geographic variations can be traced back to actions of individual patients and their healthcare providers (doctors, hospitals). These actors interact in a complicated web of shared responsibilities.

[The possibility of using the synthetic compound for the purpose of modeling of the human soft tissues in connection with the evaluation of gunshot damages].

The necessity of using a simulator of human soft tissues for the purpose of criminalistic and forensic medical expertises is dictated by the requirements put forward by the expert practice. The objective of the present study was to develop a synthetic simulator of the human soft tissues (compound) to ensure reliability of comparative criminalistics and forensic medical studies for the evaluation of gunshot injuries. The synthetic compound was prepared by mixing up the petroleum and/or synthetic oil with a polymeric thickening agent.

Improving Individual Acceptance of Health Clouds through Confidentiality Assurance.

Background: Cloud computing promises to essentially improve healthcare delivery performance. However, shifting sensitive medical records to third-party cloud providers could create an adoption hurdle because of security and privacy concerns.

Objectives: This study examines the effect of confidentiality assurance in a cloud-computing environment on individuals' willingness to accept the infrastructure for inter-organizational sharing of medical data.

The Value of Vocal Extent Measure (VEM) Assessing Phonomicrosurgical Outcomes in Vocal Fold Polyps.

Objective: This study aimed to present vocal extent measure (VEM), demonstrate its changes with phonomicrosurgical treatment in patients with vocal fold polyps (VFPs), and to compare its performance to that of established vocal parameters.

Study Design: This is an individual cohort study.

Methods: Microlaryngoscopic ablation was executed in 61 patients with manifestation of VFP (28 male, 33 female; 45 ± 13 years [mean ± SD]).

Green synthesis of water-soluble nontoxic polymeric nanocomposites containing silver nanoparticles.

New water-soluble nontoxic nanocomposites of nanosized silver particles in a polymer matrix were synthesized by a green chemistry method. Nontoxic poly(1-vinyl-1,2,4-triazole) was used as a stabilizing precursor agent in aqueous medium. Glucose and dimethyl sulfoxide were used as the silver ion-reducing agents to yield silver nanoparticles 2-26 nm and 2-8 nm in size, respectively.

[Herpesvirus infections in immunocompromised patients].

Testing of immunocompromised patients for markers of beta-herpesviruses--human herpesvirus type 6 (HHV-6) and cytomegalovirus (CMV), as well as gamma-herpesvirus--Epstein-Barr virus (EBV), revealed that all mentioned infections are frequently detected, mainlyas mixed infections. Chronic HHV-6 infection was diagnosed in more than half of the patients, whereas markers of acute phase of CMV and EBV infections were detected in 25% and 15% of patients respectively.

[Density-specific distribution of erythrocytes in different types of anemia].

Aim: To study density-specific distribution of erythrocytes (DSDE) in different types of anemia.

Material And Methods: DSDE was determined in anemic patients by fractionation of the whole blood in hematocritic capillaries in the presence of mixtures of dimethyl- and dibutylphthalates with known density.

Results: Parameters are proposed which characterize DSDE changes typical for each type of anemia: mean erythrocyte density (MED)--mean density of total erythrocytic population; DSDE width (W)--a characteristic of erythrocytic population heterogeneity; light fraction of erythrocytes (LEF)--% of the cells with density less than 1.

[Recovery of polyclonial hemopoiesis in females with chronic myeloid leukemia with a complete cytogenetic response].

Aim: To study feasibility of hemopoiesis clonality determination in assessment of remission completeness in patients with chronic myeloid leukemia (CML) using polymerase chain reaction (PCR HUMARA).

Material And Methods: We have examined 28 patients with newly diagnosed CML, 10 CML patients with a complete cytogenetic response (CCR) to therapy with imatinib mesilate and/or alpha-interferon, 24 healthy control females. Twelve patients with untreated CML were homozygous by HUMARA gene (human androgenic receptor gene) and were withdrawn from the study.

[Priorities of health-promoting and medical rehabilitation in railwaymen].

The paper describes the priorities of health-promoting and medical rehabilitation in railwaymen working under adverse industrial conditions. The authors define the priorities of selection of occupational groups to be primarily referred for sanatorium-and-spa treatment (by taking into account the profile of disease or major industry-associated risk factors), which regulate the medical criteria for selection of contingents (apparently healthy individuals having risk factors, with early morbid signs and significant forms of underlying occupational and industry-dependent diseases). The periodicity of referrals for sanatorium-and-spa treatment and health-promotion depends on the intensity of and exposure to occupational factors, as well as the mean time of development of major forms of abnormalities.

[Antibodies to the infective agents of opportunistic infections in blood of patients with hemoblastosis complicated with pneumonia].

The examination of 112 hematological patients with diagnosed acute and chronic leucosis, lymphoma, myeloma, anemia, melanoma and other diseases revealed not a single subject among these examinees in whom no markers of opportunistic infections were detected. Low titers of antibodies to Pneumocystis carinii, cytomegalovirus (CMV), Epstein-Barr virus (EBV) were noted in 42%, 46.4% and 40.

[Integral evaluation of redox metabolism in erythrocytes from patients with various anemias].

The potentiometric determination method (Vmax NADP.H) was made use of to make an integral evaluation of the status of the oxidant-restorative metabolism of erythrocytes; the method facilitates essentially the diagnostics in certain hemolytic processes like G-6-PD-insufficiency, toxic hemolytic anemia and auto-immune hemlytic anemia. Essential differences of the oxidant-restorative potential of erythrocytes (Vmax NADP.

[Contemporary approaches to diagnosis and treatment of chronic duodenitis among flying personnel].

Causes for increased gastric and duodenal morbidity were analyzed in 435 patients. Chelibacteriosis was shown to be one of the key factors of development and recurrence of chronic duodenitis which which, in its turn, leads to physical disability retirement of flying personnel. The role of determining the immune status in dynamics in predicting recurrence, and effectiveness of therapy was confirmed.

[Effects of low-intensity laser irradiation on several parameters of microcirculation in the bulbar conjunctiva of patients with scleroderma].

Computer-aided analytical system of TV images (CASTI) of the anterior segment of the eye revealed an appreciable increase of the level of aggregation gradient in arterioles and venules of the bulbar conjunctiva of 37 children suffering from various forms of scleroderma, as against 18 healthy children. Exposure to low-energy laser of a close infrared band (approximately 890 nm) had a favorable impact on blood aggregation in patients with scleroderma. CASTI of the anterior segment of the eye proved to be an objective and highly informative method for the diagnosis and monitoring of the efficacy of various treatment modalities.