Extranigral extension of structural midbrain lesions overshadows parkinsonism.

We report on a clinicoanatomical analysis of five patients with structural midbrain lesions who shared severe nigrostriatal dopaminergic denervation but presented different involuntary movements. The main clinical phenotype was parkinsonism in only one case; it was choreoballism in three cases and tremor and dystonia in one case. Structural midbrain lesions are likely to involve structures additional to nigral dopaminergic neurons.

[Approaches to occupational evaluation of allergy danger caused by work conditions].

The authors defined major criteria for allergenic danger caused by work conditions. The criteria include sensibilizing activity, intensity of chemical allergen, routes of its intake, combinations and associations with other occupational hazards and, according to hygienic classification of work and to classification of chemical allergens, to importance in causing the allergic diseases, are assessed in points. Using the criteria, considering various associations of allergies and concomitant factors and their correspondence to occurrence and severity of immunologic and allergic disorders, clinical signs of allergies (including occupational), the authors specified integral scale for evaluation of allergenic danger caused by work conditions.

[Hygienic assessment of occupational hazards resulting form low-soluble lead compounds].

The MACs for aerosols of low-soluble lead compounds should be 10 times higher than those for inorganic lead compounds.

[Allergenic properties of various natural and modified colofonies].

Natural tall colophony and its modification by monoethanolamine are moderate allergens at intracutaneous and epicutaneous ways of sensibilization reproduction. In the conditions of 30-days inhalational exposure in concentrations on the level of Limch modified by monoethanolamine colophony does not cause sensitization; while the modified tall colophony induces a weakly expressed allergic effect in experimental guinea pigs--albinos.