Publications by Erlen Cruz

Publications by authors named "Erlen Cruz"

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First report on the physicochemical and proteomic characterization of outer membrane vesicles under urine-mimicking growth conditions: comparative analysis with .

María José González Nicolás Navarro Erlen Cruz Sofía Sánchez Javier O Morales

Front Microbiol

November 2024

Article Synopsis

Uropathogenic bacteria use various techniques, like forming biofilms and producing toxins, to colonize the urinary tract and cause urinary tract infections (UTIs).
This study isolated and analyzed outer membrane vesicles (OMVs) from clinical strains under different growth conditions, revealing significant differences in protein composition related to the bacteria's adaptation to the urinary environment.
The findings suggest that OMVs play a crucial role in bacterial survival and virulence in UTIs, highlighting potential targets for future therapeutic strategies.

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Presence of intracellular bacterial communities in uroepithelial cells, a potential reservoir in symptomatic and non-symptomatic people.

Luciana Robino Rafael Sauto Cecilia Morales Nicolás Navarro María José González Erlen Cruz

BMC Infect Dis

June 2024

Background: Urinary tract infection is one of the most common infections in humans, affecting women in more proportion. The bladder was considered sterile, but it has a urinary microbiome. Moreover, intracellular bacteria (IB) were observed in uroepithelial cells from children and women with urinary tract infections (UTIs).