Selective retina therapy (SRT) for clinically significant diabetic macular edema.

Purpose: To test selective retina therapy (SRT) as a treatment of clinically significant diabetic macular edema (DME).

Methods: Prospective two-center interventional uncontrolled phase II pilot study. Thirty-nine eyes of 39 patients with previously untreated non-ischemic DME were treated with focal laser treatment using a Q-switched frequency doubled Nd:YLF laser which selectively affects the retinal pigment epithelium while sparing the photoreceptor layer.