Atomic structures and electronic properties of different contact surfaces for C F -SiO triboelectric nanogenerator based on first-principles investigations.

Modification of the dielectric friction layer materials is an ideal way to enhance the output performance of a triboelectric nanogenerator (TENG), but current research mostly focuses on the metal-polymer or metal-SiO materials. In this work, we constructed different TENG models based on polymer C F -SiO electret materials, and the electronic properties of the different contact surfaces were investigated using first principles. We found that the charge transfer in C F -SiO materials occurred only at the contact interface, and it was partially affected by the terminal atoms near the SiO interface.

Mediating role of health literacy in the relationship between social isolation and psychological distress among pre-frail older adults.

Background: Frailty has become a significant public health issue. The recent increase in the number of frail older adults has led to increased attention being paid to psychological care services in communities. The social isolation of pre-frail older adults can impact their psychological distress.

Clinical value of combining epirubicin with mindfulness intervention in patients with urinary system tumors and depression.

Background: Urinary system tumors often cause negative psychological symptoms, such as depression and dysphoria which significantly impact immune function and indirectly affect cancer prognosis. While epirubicin (EPI) is recommended by the European Association of Urology and can improve prognosis, its long-term use can cause toxic side effects, reduce treatment compliance, and increase psychological burden. Therefore, an appropriate intervention mode is necessary.

-inoculation altered the C, N contents and regulated biomass allocation in to promote plant growth and improve salt stress tolerance.

Soil salinization poses a significant ecological and environmental challenge both in China and across the globe. Plant growth-promoting rhizobacteria (PGPR) enhance plants' resilience against biotic and abiotic stresses, thereby playing a vital role in soil improvement and vegetation restoration efforts. PGPR assist plants in thriving under salt stress by modifying plant physiology, enhancing nutrient absorption, and synthesizing plant hormones.

Therapeutic effects and mechanisms of Juanbilijieqing fang in ameliorating gouty arthritis in a murine model.

This study aims to assess the safety, efficacy, and mechanisms of Juanbilijieqing Fang in a mouse model of gouty arthritis. C57BL/6 mice were allocated into six groups: control, gouty arthritis model, and treatment groups receiving varying doses of Juanbilijieqing Fang (low, medium, high), along with a positive control group treated with febuxostat. Gouty arthritis was induced via MSU crystal injection following a high-fat diet.

Risk Prediction of Liver Injury in Pediatric Tuberculosis Treatment: Development of an Automated Machine Learning Model.

Purpose: Drug-induced liver injury (DILI) is one of the most common and serious adverse drug reactions related to first-line anti-tuberculosis drugs in pediatric tuberculosis patients. This study aims to develop an automatic machine learning (AutoML) model for predicting the risk of anti-tuberculosis drug-induced liver injury (ATB-DILI) in children.

Methods: A retrospective study was performed on the clinical data and therapeutic drug monitoring (TDM) results of children initially treated for tuberculosis at the affiliated Changsha Central Hospital of University of South China.

Radiomicsmetabolic signature profiles for advanced non-small cell lung cancer with chemoimmunotherapy by reflecting biological function and survival.

Background: Resistance to chemoimmunotherapy in patients with advanced non-small cell lung cancer (NSCLC) necessitates effective prognostic biomarkers. Although F-fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) has shown potential for efficacy assessment, it has been mainly evaluated in immuno-monotherapy setting, lacking elaborations in the scenarios of immunotherapy combined with chemotherapy. To tackle this dilemma, we aimed to build a non-invasive PET/CT-based model for stratifying tumor heterogeneity and predicting survival in advanced NSCLC patients undergoing chemoimmunotherapy.

Spontaneous ventilation video-assisted thoracoscopic surgery for octogenarian non-small cell lung cancer patients: a non-inferiority study.

Background: The benefits of spontaneous ventilation (SV)-video-assisted thoracoscopic surgery (VATS) in octogenarian patients with non-small-cell lung cancer (NSCLC) have rarely been reported. This retrospective study was conducted to evaluate the safety and feasibility of SV-VATS in octogenarian patients with NSCLC.

Methods: Patients with NSCLC aged >80 years who underwent SV-VATS or mechanical ventilation (MV)-VATS between 2017 and 2022 were included in this study.

Characteristics of the immune microenvironment and their clinical significance in lung adenocarcinoma patients with different ALK fusion variants.

Background: The tumor immune microenvironment of anaplastic lymphoma kinase (ALK)-rearranged lung adenocarcinoma (LUAD) stratified by ALK fusion variants is poorly pictured. Hence, in this study, we aim to explore the immune heterogeneity of ALK LUAD across different ALK fusion variants and further investigate their significance on clinical prognosis.

Methods: A retrospective analysis was conducted on ALK LUAD patients (N=68).

Brown Carbon in East Asia: Seasonality, Sources, and Influences on Regional Climate and Air Quality.

Brown carbon (BrC) has been recognized as an important light-absorbing carbonaceous aerosol, yet understanding of its influence on regional climate and air quality has been lacking, mainly due to the ignorance of regional coupled meteorology-chemistry models. Besides, assumptions about its emissions in previous explorations might cause large uncertainties in estimates. Here, we implemented a BrC module into the WRF-Chem model that considers source-dependent absorption and avoids uncertainties caused by assumptions about emission intensities.

Establishment of an HPLC Fingerprint and Cluster Analysis for Miao Ethnic Medicine .

, a traditional Miao medicine, is commonly used by the renowned national-level Chinese Traditional Medicine practitioner Zhengshi Wu for the treatment of diarrhea due to its strong antioxidative, anti-inflammatory, and antidiarrheal effects. This study aimed to establish a high-performance liquid chromatography (HPLC) fingerprint for to provide new evidence and technical means for the scientific evaluation and effective quality control of . The procedure involved isolation with a Nano ChromCore C18 column (250 mm × 4.

Decked Out for Success: A Novel Card Game to Support School Teaching of Radioactivity and Nuclear Science.

The global nuclear skills shortage requires a comprehensive investment in training at all levels of education. With focus on post-18 and vocational education, there is a lack of resource and awareness for teaching nuclear skills to students between the ages of 11 to 18 years of age. This age group is vital if interest in this industry is to be nurtured and the skills gap is to be addressed.

A versatile reactive layer toward ultra-long lifespan lithium metal anodes.

Unstable anode/electrolyte interfaces have significantly hindered the development of lithium (Li) metal batteries under high rates and large capacities. In this study, a versatile reactive layer based on sulfur-selenium crosslinked polyacrylonitrile brushes has been developed by a combined strategy of polymer topology design and chemical crosslinking. The sulfur-selenium crosslinked polyacrylonitrile side-chains can react with Li to generate passivated LiS-LiSe-containing solid electrolyte interphase while 3D lithiophilic porous nanonetworks enable Li penetration, contributing to achieving rapid and uniform Li ion flux and a dendrite-free anode.

A tactfully designed photothermal agent collaborating with ascorbic acid for boosting maxillofacial wound healing.

Maxillofacial injuries that may cause severe functional and aesthetic damage require effective and immediate management due to continuous exposure to diverse microbial populations. Moreover, drug resistance, biofilm formation, and oxidative stress significantly impede timely bacterial removal and immune function, making the exploration of advanced materials for maxillofacial wound healing an appealing yet highly challenging task. Herein, a near-infrared photothermal sterilization agent was designed, encapsulated with liposomes and coated with ascorbic acid known for its antioxidant and immune-regulatory functions.

A bio-inspired microwave wireless system for constituting passive and maintenance-free IoT networks.

With the rapid expansion of wireless networks, the deployment and long-term maintenance of distributed microwave terminals have become increasingly challenging. To address these issues, we present a bio-inspired microwave system to constitute passive and maintenance-free wireless networks. Drawing inspiration from vertebrate skeletons and skins, we employ stimuli-responsive polymer with tunable stiffness to support and protect sensitive electromagnetic structures, and synthesize self-healable skin-like polymer for system encapsulation.

Conjugated phthalocyanine-based framework as artificial SEI for over 400 Wh kg lithium-metal battery.

High-voltage lithium-metal batteries (HVLMBs) are appealing candidates for next-generation high-energy rechargeable batteries, but their practical applications are still limited by the severe capacity degradation, attributed to the poor interfacial stability and compatibility between the electrode and the electrolyte. In this work, a 2D conjugated phthalocyanine framework (CPF) containing single atoms (SAs) of cobalt (CoSAs-CPF) is developed as a novel artificial solid-electrolyte interphase (SEI) in which a large amount of charge is transferred to the CPF skeleton due to the Lewis acid activity of the Co metal sites and the strong electron-absorbing property of the cyano group (-CN), greatly enhancing the adsorption of the Li and regulating the Li distribution toward dendrite-free LMBs, which are superior to most of the reported SEI membranes. As a result, the Li||Li symmetrical cell with CoSAs-CPF-modified Li anodes (CoSAs-CPF@Li) exhibits a low polarization with an area capacity of 1.

Metabolic response to burn injury: a comprehensive bibliometric study.

Objective: Burns lead to systemic changes manifested by systemic disturbances in water-electrolyte balance and systemic metabolic and inflammatory responses. The hypermetabolic response after a burn injury relies on metabolic, hormonal, and inflammatory dysregulation mechanisms. This study aimed to provide a comprehensive bibliometric analysis of the burn metabolism research field, identifying key trends, influential contributors, and emerging research hotspots to inform future investigative efforts.

Diagnostic value of lung function tests in long COVID: analysis of positive bronchial provocation test outcomes.

Background: Long COVID patients are prone to bronchial hyperresponsiveness and respiratory symptoms like coughing and breathing difficulties, often with positive bronchial provocation test (BPT) results.

Objective: This study aims to evaluate the diagnostic value of various lung function tests in patients with long-term COVID-19, explicitly focusing on positive BPT outcomes.

Methods: Our study analyzed the BPT outcomes and various pulmonary function parameters of all 9,406 COVID-19 patients who met the inclusion criteria and visited our hospital between February 24, 2022, and April 28, 2024.

Novel and (Tubeufiaceae, Tubeufiales) species from terrestrial habitats in China and Thailand.

During our investigations of saprobic fungi, five fungal collections from terrestrial habitats in China and Thailand were examined using both morphological and multi-gene phylogenetic approaches (LSU, ITS, 1-α, and 2), resulting in the identification of three novel species: , , and . and are morphologically similar in their asexual morphs but can be distinguished based on their molecular phylogenetic data. In this study, our new species, , represents the fourth sexual species within the genus, characterized by yellow-brown ascomata and fusiform ascospores.

Protective effects and possible mechanisms of mesenchymal stem cells and mesenchymal stem cell-derived extracellular vesicles against kidney fibrosis in animal models: a systematic review and meta-analysis.

Introduction: The risk of kidney fibrosis is significantly elevated in individuals with diabetes, chronic nephritis, trauma, and other underlying conditions. Concurrently, human umbilical cord blood-derived mesenchymal stem cells (hUCB-MSCs) and their extracellular vesicles (MSC-Exos) have gained prominence in regenerative medicine. In light of these observations, we are undertaking a meta-analysis to elucidate the influence of hUCB-MSCs and MSC-Exos on kidney fibrosis.

Association between metabolic score for insulin resistance and stroke: a nationally representative cross-sectional study from NHANES 2007-2018.

Background: Stroke is a significant cerebrovascular disease and remains one of the leading causes of death and disability worldwide. Insulin resistance has been strongly linked to the incidence of stroke. Employing characteristics of metabolic syndrome, the Metabolic Score for Insulin Resistance (METS-IR) accurately measures insulin resistance.

The association between sleep duration and myopia among Chinese school-age students: mediation effect of physical activity.

Background: This study aimed to investigate the relationship between sleep duration and myopia in school-age students, as well as to observe the role of physical activity as a mediating variable in sleep duration and myopia.

Methods: Using multistage stratified sampling, 26,020 school-age students in Jiangsu Province, ages 7-18, were selected for this cross-sectional survey. Each participant completed a standardized interview in which their were asked about their vision, level of physical activity and average hours of sleep per day over the past month.

Green space is associated with new-onset stroke among Chinese middle-aged and older adults: data from China Health and Retirement Longitudinal Study (CHARLS).

Background And Aims: The relationship between green space and new-onset stroke is inconclusive. This study aimed to investigate the association between green space and stroke risk among Chinese middle-aged and older adults.

Methods: Data were taken from participants aged ≥45 years in the China Health and Retirement Longitudinal Study (CHARLS).

Metabolic engineering of for high-level production of pneumocandin B.

Pneumocandin B (PB) is a lipohexapeptide synthesized by and serves as the precursor for the widely used antifungal drug caspofungin acetate (Cancidas®). However, the low titer of PB results in fermentation and purification costs during caspofungin production, limiting its widespread clinical application. Here, we engineered an efficient PB-producing strain of by systems metabolic engineering strategies, including multi-omics analysis and multilevel metabolic engineering.

Efficacy of Modified Electroconvulsive Therapy in Treatment-Resistant Schizophrenia.

Objective: The aim of the study was to investigate the therapeutic effects of modified electroconvulsive therapy (MECT) in combination with risperidone tablets and psychotherapy in the treatment of patients with treatment-resistant schizophrenia (TRS).

Methods: Patients with TRS admitted to the psychiatric department of our hospital between January 2018 and December 2019 were selected as study participants. They were randomly divided into a control group and a study group, with the control group receiving risperidone tablets and psychotherapy, and the study group undergoing MECT as well as the control group treatment.