Melatonin reduces projection neuronal injury induced by 3-nitropropionic acid in the rat striatum.

Background: Melatonin has shown a protective effect against various oxidative damages in the nervous system. Our previous studies have also confirmed its effect on behavioral dysfunction of experimental rats and injury of striatal interneurons induced by 3-nitropropionic acid. The present study aimed to further determine the effect of melatonin on the injury of striatal projection neurons induced by 3-nitropropionic acid.

Does diffusion tensor data reflect pathological changes in the spinal cord with chronic injury.

Magnetic resonance diffusion tensor imaging has been shown to quantitatively measure the early pathological changes in chronic cervical spondylotic myelopathy. In this study, a novel spongy polyurethane material was implanted in the rat C3-5 epidural space to establish a rat model of chronic cervical spondylotic myelopathy. Diffusion tensor data were used to predict pathological changes.

Is the speed of chronic compression an important factor for chronic spinal cord injury rat model?

Objective: To evaluate the effect of expansion speed on chronic compressive spinal cord injury in the rat.

Methods: Thirty-six Sprague-Dawley rats were divided into four groups: a control group, a group receiving compressor in the C5-C6 epidural space with instant compression (group 1), and two other groups receiving water-absorbing polyurethane polymer sheets with two expansion speeds, which reached maximum volume in 2 h (group 2: fast expansion) or 24 h (group 3: slow expansion). A C6 laminectomy was performed in the control group.

3-T imaging of the cranial nerves using three-dimensional reversed FISP with diffusion-weighted MR sequence.

Purpose: To depict the normal anatomy of cranial nerves in detail and define the exact relationships between cranial nerves and adjacent structures with three-dimensional reversed fast imaging with steady-state precession (FISP) (3D-PSIF) with diffusion-weighted MR sequence.

Materials And Methods: 3D-PSIF with diffusion-weighted MR sequence was performed and axial images were obtained in 22 healthy volunteers. Postprocessing techniques were used to generate images of cranial nerves, and the images acquired were compared with anatomical sections and textbook diagrams.