Publications by authors named "Erison Santana Dos Santos"

Article Synopsis
  • This systematic review investigated the connection between oncoviruses and head and neck cancers (HNC).
  • Researchers analyzed studies from five databases and assessed their reliability using established guidelines.
  • The findings revealed a significant relationship between certain oncoviruses, particularly HPV-16, HPV-18, and Epstein-Barr virus, and the development of HNC, while further research is needed on other viruses like human cytomegalovirus and Merkel Cell Polyomavirus.
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Objectives: To describe the historical evolution and dissemination of the Oral Medicine and Oral and Maxillofacial Pathology international societies and associations across the globe, and to provide insights into their significant contributions toward oral health promotion.

Study Design: This review was conducted in accordance with the JBI Scoping Review Methodology Group guidance. The reporting followed the Preferred Reporting Items for Systematic Reviews extension for Scoping Reviews (PRISMA-ScR).

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Article Synopsis
  • Pierre Fauchard, known as the father of dentistry, made significant contributions to various dental fields, although his impact on oral medicine and maxillofacial pathology was previously overlooked.
  • This study aimed to uncover Fauchard’s work on oral diseases by analyzing both French and English sources, gathering information on diagnosed and treated conditions.
  • The research identified his contributions to diseases like scurvy, abscesses, and oral ulcers, highlighting his importance in diagnosing and treating various oral health issues relevant to modern dentistry.
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Objective: To assess the clinical scenarios in which nerve blocks are employed in the context of burning mouth syndrome (BMS).

Study Design: This scoping review followed the PRISMA-ScR. A protocol was generated on Open Science Framework.

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Cancer disclosure represents a complex healthcare dynamic. Physicians or caregivers may be prompted to withhold diagnosis information from patients. This study aims to comprehensively map and synthesize available evidence about diagnosis nondisclosure regarding head and neck cancer (HNC) patients.

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Objective: Histopathological grading of oral epithelial dysplasia (OED) is the current standard for stratifying cancer progression risk but is associated with subjectivity and variability. This problem is not commonly seen regarding the grading of epithelial dysplasia in other sites. This systematic review aims to compare grading systems for oral, anal, penile, and cervical epithelial dysplasia to determine their predictive accuracy for recurrence and malignant transformation (MT) outcomes.

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Aims: We conducted a systematic review of post-test communication protocols and observational studies regarding counseling for a positive sexually transmitted infection (STI) result and also discuss the role of dental specialist (e.g., oral medicine) in this sense.

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Colonialism's enduring impact on Brazil has had significant implications for health and oncology outcomes. This historical essay delves into the profound changes brought about by the transatlantic slave trade from Africa to the Americas, particularly in terms of its influence on the economy, sociocultural habits, and health outcomes. This essay explores the enduring connections between the colonial period's operational dynamics in Brazil and the current epidemiological panorama of head and neck cancer (HNC).

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Cancer is a significant cause of death, precluding increasing life expectancy worldwide. That is a multifactorial disease initiated by intrinsic or extrinsic factors that induce cell differentiation into cancer cells. However, cancer development, progression, and metastasis are not controlled only by cancer cells.

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The search for biomarkers associated with oral leukoplakia malignant transformation is critical for early diagnosis and improved prognosis of oral cancer patients. This systematic review and meta-analysis aimed to assess protein-based markers potentially associated with malignant transformation of oral leukoplakia. Five database and the grey literature were searched.

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This study aimed to map systemic alterations predisposing to oral squamous cell carcinoma (OSCC) onset. This review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses. Five databases were used to access (1) reports of OSCC co-occurring in patients with systemic conditions, (2) prevalence of OSCC among these patients, and (3) clinicopathological profiles.

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Objective: To integrate all the available data published in the English literature regarding the protein diagnostic and/or prognostic markers in salivary gland tumors identified by mass spectrometry (MS)-based discovery proteomics.

Design: An extensive search was carried out using MEDLINE/PubMed, EMBASE, Web of Science, and Scopus databases. Manual searching in Google Scholar and assessment of the reference list of the included articles also was performed.

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Head and neck cancer is globally challenging due to the resistance to therapy and aggressive behavior leading to high rates of mortality. Recent findings show that the tumor microenvironment plays a role in the maintenance and progression of many solid tumors, including head and neck cancer. The mechanisms involved in the modulation and regulation of the tumor microenvironment remain poorly understood.

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In numerous types of cancer, the primary tumor site can show a correlation with disease behavior and survival outcomes. In salivary gland tumors (SGTs) this association remains controversial. This study assessed the association between primary sites of SGTs and prognosis.

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Purpose: Different levels of miRNA expression have been described in salivary gland tumors as a potential diagnostic marker and predictor of survival. We systematically reviewed the literature to assess the diagnostic and prognostic value of miRNAs on salivary gland tumors.

Methods: An electronic search was conducted in PubMed, Scopus, Embase, Cochrane, and Web of Science databases.

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Objective: This systematic review aimed to evaluate the epidemiologic profile, screen for possible risk factors, and evaluate the spectrum of clinical characteristics of oral squamous cell carcinoma (OSCC) around dental implants (DIs).

Methods: The systematic review was performed according to the Preferred Reporting Items for Systematic Reviews and Meta- Analyses statement.

Results: Thirty-three articles met the eligibility criteria.

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Article Synopsis
  • - Osteopontin (OPN) is a protein that interacts with calcium and is crucial for various bodily functions, particularly in bone cell activities and mineralization, but it also plays a role in diseases like cancer and atherosclerosis.
  • - Research indicates that OPN may contribute to the development of oral cancer by promoting aggressive cell behaviors through the PI3K/AKT/mTOR signaling pathway, which can enhance cell growth, invasion, and resistance to treatment.
  • - The text reviews the mechanisms by which OPN is involved in oral cancer and explores its potential use in clinical settings for diagnosis and prognosis of the disease.
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Article Synopsis
  • MCs (mast cells) are linked to disease progression and may influence conditions like tumors, but their exact role in odontogenic lesions like ameloblastomas (AMBs) and odontogenic keratocysts (OKCs) is unclear.
  • A study analyzed 40 odontogenic lesions (20 OKCs and 20 AMBs) using histological methods and statistical analysis to assess the presence and impact of MCs in these conditions.
  • Results showed that MCs were found more frequently in OKCs (60%) than in AMBs (35%), with significant differences between solid and unicystic AMBs, indicating potential roles for MCs but no definitive conclusions on their biological influence overall.
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