Publications by authors named "Erini Pectasides"
Gemcitabine and pegylated liposomal doxorubicin alternating with cisplatin plus cyclophosphamide in platinum refractory/resistant, paclitaxel-pretreated, ovarian carcinoma.
Dimitrios Pectasides Nicolaos Xiros George Papaxoinis Gerasimos Aravantinos Constantinos Sykiotis Erini Pectasides
Gynecol Oncol
January 2008
Article Synopsis
- This phase II study examined the effectiveness and safety of a chemotherapy regimen combining gemcitabine and pegylated liposomal doxorubicin with cisplatin and cyclophosphamide in patients with tough-to-treat ovarian cancer.
- Out of 48 patients, 37.5% showed objective responses, with significant improvements in CA125 levels for 71.4% of those tested, leading to a median progression-free survival of 6.9 months and overall survival of 18.2 months.
- The chemotherapy was generally well tolerated, although some patients experienced side effects like myelosuppression and nausea, and many required additional support due to complications.