A Computable Definition of Sepsis Facilitates Screening and Performance Improvement Tracking.

Background: Sepsis kills almost 5,000 children annually, accounting for 16% of pediatric health care spending in the United States.

Objectives: We sought to identify sepsis within the Electronic Health Record (EHR) of a quaternary children's hospital to characterize disease incidence, improve recognition and response, and track performance metrics.

Methods: Methods are organized in a plan-do-study-act cycle.

A retrotransposon-mediated gene duplication underlies morphological variation of tomato fruit.

Edible fruits, such as that of the tomato plant and other vegetable crops, are markedly diverse in shape and size. SUN, one of the major genes controlling the elongated fruit shape of tomato, was positionally cloned and found to encode a member of the IQ67 domain-containing family. We show that the locus arose as a result of an unusual 24.