[Stratification of the risk of malignization of intraductal papillary mucinous neoplasms of the pancreas].

The purpose of this review was to analyze the most perspective methods for risk stratification of malignant transformation of pancreatic intraductal papillary mucinous neoplasms (IPMN). Advisability of humoral predictors (tumor markers, inflammatory markers, circulating leptin and branched-chain amino acids, etc.) is in identifying prognostic signs suitable for risk stratification of IPMN malignant transformation and, therefore, determining treatment strategy for a particular patient.

[Features and results of minimally invasive treatment of recurrent achalasia].

Objective: To evaluate the early and long-term postoperative outcomes in patients with recurrent achalasia, as well as the main features of surgical treatment.

Material And Methods: There were 7 patients (4 men and 3 women) with recurrent achalasia. Mean age of patients was 42.

[Esophageal achalasia: possible pathogenic concepts from the perspective of modern notions].

Esophageal achalasia is an esophageal motility disease characterized by impaired relaxation of lower esophageal sphincter (LES) and severe clinical symptoms. The main etiological factors and other essential aspects of pathogenesis and progression of this disorder are actively studied. To date, the question of significance of etiological factors is experimental and requires further study.

[Results of 300 pancreatic duct stenting in acute pancreatitis].

Objective: To analyze the results of pancreatic duct stenting in moderate and severe forms of pancreatitis.

Material And Methods: Pancreatic duct stenting in 300 patients with acute pancreatitis was analyzed. Examination and treatment were carried out in accordance with national clinical guidelines for acute pancreatitis (2015).

Effect of a Residual Biofilm on Release of Transforming Growth Factor β1 from Dentin.

Introduction: Several studies have reported regeneration of the pulp-dentin complex when treating noninfected root canal systems. However, current protocols applied to infected root canal systems are much less predictable for the formation of dentin. Converging lines of evidence implicate residual biofilm as an important factor for these variable histologic outcomes.

[Redo laparoscopic surgery for recurrent gastroesophageal reflux disease and hiatal hernia].

Aim: To assess mechanisms of recurrent gastroesophageal reflux disease and the ability to perform adequate surgical correction after previous surgery.

Material And Methods: The authors from various surgical centers have operated 2678 patients with gastroesophageal reflux disease and hiatal hernia for the period 1993-2018. 127 (4.