Publications by authors named "Erin N Schuette"
Nat Cardiovasc Res
January 2023
Article Synopsis
- Cardiac cell surface proteins can serve as both drug targets and biomarkers, distinguishing different cell types and disease states.
- The research developed a platform called CellSurfer to quantitatively profile cell surface proteins in limited cell samples, specifically isolating primary human heart cells.
- Key findings include the identification of LSMEM2, a protein specific to healthy heart cells, and significant differences in surface protein abundance between healthy and failing cardiomyocytes, which could aid drug discovery and disease research.
