Effect of class III and class IV obesity on oocyte retrieval complications and outcomes.

Objective: To assess the effect of class III (body mass index [BMI] 40-49.9 kg/m) and class IV obesity (BMI ≥ 50 kg/m) on oocyte retrieval complications and outcomes.

Design: Cohort study.

Use of imaging software for assessment of the associations among zona pellucida thickness variation, assisted hatching, and implantation of day 3 embryos.

Purpose: The aim of this study was to determine if zona pellucida thickness variation (ZPTV) is associated with implantation and if this relationship changes with use of assisted hatching (AH).

Methods: Day 3 embryos from single or double embryo transfers (DETs) performed between 2014 and 2016 were included. ZPTV was assessed by examining photographs taken before transfer using an automated image processing platform to segment the zona pellucida (ZP) with an active contour technique.

Public support in the United States for elective oocyte cryopreservation.

Objective: To determine whether public support for oocyte cryopreservation (OC) exists and if support varies by demographic factors.

Design: Cross-sectional electronic survey.

Setting: Not applicable.

The Role of Hysteroscopic and Robot-assisted Laparoscopic Myomectomy in the Setting of Infertility.

Fibroids, the most common gynecologic condition in women of reproductive age, have traditionally been treated with hysterectomy. As more women delay childbearing, myomectomy becomes an essential component of the gynecologist's armamentarium. Minimally invasive approaches to myomectomy have been shown to decrease morbidity and reduce care-related costs, while improving reproductive outcomes.

Robotic single-site myomectomy: a step-by-step tutorial.

Objective: To provide a step-by-step description of our published technique of single-site robot-assisted laparoscopic myomectomy with the goal of promoting its safe adoption.

Design: Surgical video tutorial.

Setting: University medical center.

Robotic single-site myomectomy: initial report and technique.

Objective: To report the first cases of robotic single-site (RSS) myomectomy with the use of the Da Vinci Si Surgical System with wristed semirigid instrumentation.

Design: Case series.

Setting: University hospital.

Treatment of premenstrual dysphoric disorder.

Premenstrual dysphoric disorder (PMDD) is comprised of a cluster of affective, behavioral and somatic symptoms recurring monthly during the luteal phase of the menstrual cycle. The disorder affects 3-8% of menstruating women and represents the more severe and disabling end of the spectrum of premenstrual disorders, which includes premenstrual syndrome and premenstrual aggravation of underlying affective disorder. Rigorous and specific diagnostic criteria for PMDD were specified in the Diagnostic and Statistical Manual of Mental Disorders IV (1994) and reaffirmed in the Diagnostic and Statistical Manual of Mental Disorders V (2013) and, consequently, there has been a marked increase in well-designed, placebo-controlled studies evaluating treatment modalities.

Novel hormone treatment of benign metastasizing leiomyoma: an analysis of five cases and literature review.

Objective: To evaluate novel hormonal therapies in patients with unresectable benign metastasizing leiomyoma (BML) disease.

Design: Case series.

Setting: National Institutes of Health (NIH).

Breast cancer close to the nipple: does this increase the risk of nodal metastasis at diagnosis?

Background: Previous studies of patients with invasive breast cancer examined, with mixed results, tumour location as a predictor of axillary lymph node metastasis. This study assessed whether tumour location in relation to the nipple impacts the presence of axillary lymph node metastasis at the time of diagnosis.

Methods: A retrospective review was undertaken of the medical records and available imaging of 285 patients diagnosed with invasive breast cancer between January 2001 to June 2007 at Boston University Medical Center.