Purpose Of Review: To review neurologic complications of common and recently developed chemotherapeutic agents, as well as recent research regarding 'chemobrain'.
Recent Findings: Bortezomib, a new anticancer agent, has a propensity toward causing a largely sensory and reversible peripheral neuropathy. Infusion of magnesium and calcium pre and post-oxaliplatin infusion reduces neuropathy but may interfere with clinical response to oxaliplatin.