Well executed multicenter clinical trials often provide significant evidence and support for, or against, foundational aspects of clinical procedures perceived to improve clinical management of a medical condition. In this review, discussed are reports of multicenter clinical trials designed to investigate sentinel lymph node biopsy procedures in seven types of cancer: breast, melanoma, head and neck, gastric, colon, uterine, and vulvar-with focus on the most recent reports of the hypotheses, objectives, parameters, data, results, implications, and impacts of the included trials. Such trials generally enroll more subjects, in shorter time periods, than do single-center studies.
View Article and Find Full Text PDFMolecular imaging of infection has evolved since its inception. This articles covers a number of infectious processes, including osteomyelitis, diabetic foot infections, periprosthetic infections, cardiovascular infections (including those due to implantable devices), abdominal infections, and fever of unknown origin. Planar, SPECT, SPECT/CT, F-FDG PET/CT, and PET/MRI are also discussed.
View Article and Find Full Text PDFObjective: The objective of our study was to study patterns of services rendered by U.S. physicians who self-identify as nuclear medicine (NM) specialists.
View Article and Find Full Text PDF