Publications by authors named "Erin D Gonzales"
Article Synopsis
- The phytopathogen studied has an ortholog of a surface layer protein (NpdA), but does not produce a traditional S-layer; the study aimed to confirm S-layer formation and its effects on virulence and other traits.
- Experimental confirmations showed that the pathogen AAC00-1 does form an NpdA-based S-layer but did not exhibit any significant differences in virulence compared to the mutant strain in watermelon fruit tests.
- NpdA orthologs were found in multiple strains of Betaproteobacteria and Gammaproteobacteria, suggesting that this new S-layer family plays a role in various Pseudomonadota, with potential implications for biofilm formation and material movement between cells.
Huntington's disease (HD) is a progressive neurological disorder whose non-motor symptoms include sleep disturbances. Whether sleep and activity abnormalities are primary molecular disruptions of mutant Huntingtin (mutHtt) expression or result from neurodegeneration is unclear. Here, we report Drosophila models of HD exhibit sleep and activity disruptions very early in adulthood, as soon as sleep patterns have developed.
View Article and Find Full Text PDFCREB-responsive transcription has an important role in adaptive responses in all cells and tissue. In the nervous system, it has an essential and well established role in long-term memory formation throughout a diverse set of organisms. Activation of this transcription factor correlates with long-term memory formation and disruption of its activity interferes with this process.
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