MRI-derived proton density fat fraction.

Reflecting the growing interest in early diagnosis of nonalcoholic fatty liver disease in recent years, the development of noninvasive and reliable fat quantification methods is required. Fat quantification by magnetic resonance imaging (MRI), especially MRI-derived proton density fat fraction (MRI-PDFF) obtained by quantitative chemical shift imaging such as the multi-point Dixon method, is highly correlated with histological evaluation and fat quantification with MR spectroscopy (MRS). In recent years, MRI-PDFF has been increasingly used as a reference standard for image-based fat quantification instead of MRS because it is possible to evaluate the whole liver with a single breath-hold.

Quantitative assessment of liver steatosis using ultrasound: dual-energy CT.

Reflecting the growing interest in early diagnosis of non-alcoholic fatty liver disease in recent years, the development of noninvasive and reliable fat quantification methods is needed. Dual-energy computed tomography (DE-CT) is a quantitative diagnostic imaging method that estimates the composition of the imaging target using a material decomposition technique based on the X-ray absorption characteristics peculiar to substances from DE-CT scanning using X-rays generated with different energies (tube voltage). In this review article, we first explain the basic principles and technical aspects of DE-CT.

Dynamic contrast-enhanced computed tomography diagnosis of primary liver cancers using transfer learning of pretrained convolutional neural networks: Is registration of multiphasic images necessary?

Purpose: To evaluate the effect of image registration on the diagnostic performance of transfer learning (TL) using pretrained convolutional neural networks (CNNs) and three-phasic dynamic contrast-enhanced computed tomography (DCE-CT) for primary liver cancers.

Methods: We retrospectively evaluated 215 consecutive patients with histologically proven primary liver cancers, including six early, 58 well-differentiated, 109 moderately differentiated, 29 poorly differentiated hepatocellular carcinomas (HCCs), and 13 non-HCC malignant lesions containing cholangiocellular components. We performed TL using various pretrained CNNs and preoperative three-phasic DCE-CT images.

Improvement in radiological reading efficiency and residents' education and clinical contribution using the modified reading system "Triage Reader".

Purpose: To assess whether the modified reading system "Triage Reader" (TR) can improve the radiological reading work environment.

Materials And Methods: This retrospective, single-center study analyzed two reading systems for 26,786 computed tomography and magnetic resonance imaging examinations. In the conventional system (January 1-May 31, 2016), all reading work was mostly completed within the day.

Outcomes of uterine cervical cancer patients with pelvic lymph node metastases after radiotherapy without boost irradiation of metastases.

Aim: The aim of this study was to evaluate the outcomes of uterine cervical cancer patients with pelvic lymph node (PLN) metastases after radiotherapy without boost irradiation of the metastases and to clarify the necessity of the boost irradiation of metastatic lesions.

Methods: Thirty-two patients with uterine cervical cancer metastasizing only to the PLN were treated with definitive radiotherapy without boost irradiation of the metastases between 2008 and 2012 at our institution and were selected for this study. The pattern of progression, overall survival, and progression-free survival were analyzed.

Palliative radiotherapy for Japanese patients with malignant melanoma: a single-institution experience.

Purpose: This study aimed to clarify the significance of palliative radiotherapy for Japanese patients with malignant melanoma based on the experience of our institution.

Materials And Methods: Twenty-nine patients with malignant melanoma who underwent palliative radiotherapy at our facility were included in the investigation. Median radiation dose was 30 Gy (4-30).

BPG3 is a novel chloroplast protein that involves the greening of leaves and related to brassinosteroid signaling.

Brassinosteroids are plant steroid hormones that regulate plant organs and chloroplast development. The detailed molecular mechanism for plant development by BR signaling is yet to be revealed, and many points regarding the relationship between BR signaling and chloroplast development remain unknown. We identify here the dominant mutant Brz-insensitive-pale green3-1D (bpg3-1D) from the Arabidopsis FOX lines that show reduced sensitivity to the chlorophyll accumulation promoted by the BR biosynthesis inhibitor, Brassinazole (Brz), in the light.

Validity of reduced radiation dose for localized diffuse large B-cell lymphoma showing a good response to chemotherapy.

To evaluate the validity of a decrease in the radiation dose for patients who were good responders to chemotherapy for localized diffuse large B-cell lymphoma (DLBCL), 91 patients with localized DLBCL who underwent radiotherapy after multi-agent chemotherapy from 1988-2008 were reviewed. Exclusion criteria were as follows: central nervous system or nasal cavity primary site, or Stage II with bulky tumor (≥10 cm). Of these patients, 62 were identified as good responders to chemotherapy.