Co-culturing experiments reveal the uptake of myo-inositol phosphate synthase (EC 5.5.1.4) in an inositol auxotroph of Saccharomyces cerevisiae.

Background: Myo-Inositol Phosphate Synthase (MIP) catalyzes the conversion of glucose 6- phosphate into inositol phosphate, an essential nutrient and cell signaling molecule. Data obtained, first in bovine brain and later in plants, established MIP expression in organelles and in extracellular environments. A physiological role for secreted MIP has remained elusive since its first detection in intercellular space.

Development of a Tool to Assess Trainees' Ability to Design and Conduct Quality Improvement Projects.

An important competency for residents developing skills in quality improvement (QI) and patient safety (PS) is to independently carry out an improvement project. The authors describe the development and reliability testing of the Quality Improvement Project Evaluation Rubric (QIPER) for use in rating project presentations in the Department of Veterans Affairs Chief Resident in Quality and Safety Program. QIPER contains 19 items across 6 domains to assess competence in designing, implementing, analyzing results of, and reporting on a QI/PS project.