APOE and LDLR Gene Polymorphisms and Dyslipidemia Tracking. Rio de Janeiro Study.

Background: Studies show an association between changes in apolipoprotein E (ApoE) and LDLR receptor with the occurrence of dyslipidemia.

Objectives: To investigate the association between polymorphisms of the APOE (ε2, ε3, ε4) and LDLR (A370T) genes with the persistence of abnormal serum lipid levels in young individuals followed up for 17 years in the Rio de Janeiro Study.

Methods: The study included 56 individuals (35 males) who underwent three assessments at different ages: A1 (mean age 13.

Blood pressure in adolescence, adipokines and inflammation in young adults. The rio de janeiro study.

Background: The impact of blood pressure (BP) during adolescence on other cardiovascular risk factors in young adults is important for the primary prevention.

Objective: To evaluate BP, anthropometric indexes, metabolic and inflammatory profiles in young individuals stratified by their BP behavior recorded for 18 years.

Methods: A total of 116 individuals, of whom 63 were males, from the Rio de Janeiro study (follow-up of 17.

Renal sympathetic denervation for resistant hypertension treatment : current perspectives.

The authors review the concept of resistant hypertension and the involvement of the sympathetic nervous system in hypertension as a rational basis for the technique of renal sympathetic denervation (RSD) performed percutaneously. This revision is the result of an active search for scientific articles with the term "renal denervation" in the Medline and PubMed databases. The techniques and devices used in the procedure are presented, as well as clinical outcomes at six, 12 and 24 months after the intervention with the Symplicity catheter.

Pulse wave velocity, blood pressure and adipocytokines in young adults: the Rio de Janeiro study.

Background: Data on noninvasive vascular assessment and their association with cardiovascular risk variables are scarce in young individuals.

Objective: To evaluate the association between pulse wave velocity and blood pressure, anthropometric and metabolic variables, including adipocytokines, in young adults.

Methods: A total of 96 individuals aged 26 to 35 years (mean 30.

Association between uric acid and cardiovascular risk variables in a non-hospitalized population.

Background: The association between uric acid (UA) and cardiovascular risk variables remains a controversial issue in epidemiological studies.

Objective: To evaluate the association between UA, blood pressure (BP), anthropometric indices and metabolic variables in a non-hospitalized population stratified by UA quintiles.

Methods: A cross-sectional observational study evaluated 756 individuals (369 males), aged 50.

Overweight and cardiovascular risk among young adults followed-up for 17 years: the Rio de Janeiro study, Brazil.

Background: The adoption of primary prevention measures among young people has a favorable impact on the context of cardiovascular diseases.

Objective: To assess blood pressure (BP) and cardiovascular risk variables among young adults stratified according to the body mass index (BMI) behavior obtained along 17 years, since childhood/adolescence (C/A).

Methods: Three assessments were carried out in 115 individuals pertaining to the study cohort of Rio de Janeiro, Brazil.

Blood pressure in young individuals as a cardiovascular risk marker. The Rio de Janeiro study.

Background: The study of the cardiovascular risk variables in young populations is fundamental to establish primary prevention strategies.

Objective: To evaluate the blood pressure (BP), anthropometric and metabolic profile in young individuals from The Rio de Janeiro Study, followed by 17 years.

Methods: A total of 115 individuals (64 males) were evaluated at three different moments (follow-up: 212.